Dr. Isabelle Audo, MD, PhD
Claim this profileCHNO XV-XX Paris - CIC 1423
Area of expertise
Retinitis Pigmentosa
Isabelle Audo, MD, PhD has run 6 trials for Retinitis Pigmentosa. Some of their research focus areas include:
None
Isabelle Audo, MD, PhD has run 2 trials for None. Some of their research focus areas include:
Clinical Trials Isabelle Audo, MD, PhD is currently running
Natural History Study
for Best Disease
The purpose of this study is to establish the natural history of of participants with BESTROPHIN 1 Vitelliform Macular Dystrophy. The blinding disorder Best Vitelliform Macular Dystrophy (VMD) is caused by any one of more than 250 different mutations in the BEST1 gene. As new treatments are developed, a clear understanding of the natural history of disease progression of BEST1 VMD is necessary. The goals of this natural history study are to: 1. Report the natural history of retinal degeneration in participants with a clinical diagnosis of VMD with molecular confirmation of a pathogenic BEST1 mutation(s). 2. Identify sensitive structural and functional outcome measures to use for future multicenter clinical trials for the treatment of BESTROPHIN 1 VMD. 3. Compare progression of the identified structural and functional measures between the two eyes to judge the suitability of the second untreated eye as a control for a future clinical trial involving unilateral treatment 4. Identify well-defined patient populations for future clinical trials of investigative treatments for BEST1 VMD.
Recruiting
1 award
N/A
2 criteria
Gene Therapy
for Retinitis Pigmentosa
Mutations in the rod-expressed gene, cyclic nucleotide-gated channel beta subunit (CNGB1) and associated inborn errors in metabolism are causes of retinal disease that causes progressive loss of vision. Retinitis pigmentosa (RP) is a major cause of untreatable blindness associated with CNGB1 (CNGB1-RP). RP involves the death of photoreceptor cells that can be caused by mutations in a number of different genes. Treatment by gene therapy could prevent blindness in cases of inherited retinal dystrophies including RP. In the future RP due to mutations in CNGB1 may be treatable by gene therapy since this form of photoreceptor degeneration involves a slow loss of rod photoreceptor cells. This provides a wide window of opportunity for the identification of patients and initiation of treatment. Our efforts are directed toward developing gene therapy as a treatment. To this end, our objective is to better understand the disease process of CNGB1-RP and other allied inherited disorders so that we can develop clinical tests to measure the outcomes of treatment.
Recruiting
1 award
N/A
2 criteria
More about Isabelle Audo, MD, PhD
Clinical Trial Related
4 years of experience running clinical trials · Led 6 trials as a Principal Investigator · 3 Active Clinical Trials
Treatments Isabelle Audo, MD, PhD has experience with
- AAV5-RPGR
- Mobility Test
- Ophthalmic Examination
- Ophthalmic Examinations
- CNGB1 Gene Therapy
- SPVN06
Breakdown of trials Isabelle Audo, MD, PhD has run
Retinitis Pigmentosa
Retinal Disease
Retinal Dystrophy
Sudden Visual Loss
Other Doctors you might be interested in
Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Isabelle Audo, MD, PhD specialize in?
Isabelle Audo, MD, PhD focuses on Retinitis Pigmentosa and None. In particular, much of their work with Retinitis Pigmentosa has involved PR positive patients, or patients who are RHO positive.
Is Isabelle Audo, MD, PhD currently recruiting for clinical trials?
Yes, Isabelle Audo, MD, PhD is currently recruiting for 3 clinical trials in the USA. If you're interested in participating, you should apply.
Are there any treatments that Isabelle Audo, MD, PhD has studied deeply?
Yes, Isabelle Audo, MD, PhD has studied treatments such as AAV5-RPGR, Mobility Test, Ophthalmic examination.
What is the best way to schedule an appointment with Isabelle Audo, MD, PhD?
Apply for one of the trials that Isabelle Audo, MD, PhD is conducting.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
Unbiased Results
We believe in providing patients with all the options.
Your Data Stays Your Data
We only share your information with the clinical trials you're trying to access.
Verified Trials Only
All of our trials are run by licensed doctors, researchers, and healthcare companies.