Dr. Howland Crosswell
Claim this profileSaint Francis Cancer Center
Area of expertise
Hodgkin's Lymphoma
Howland Crosswell has run 4 trials for Hodgkin's Lymphoma. Some of their research focus areas include:
Leukemia
Howland Crosswell has run 3 trials for Leukemia. Some of their research focus areas include:
Affiliated Hospitals
Saint Francis Hospital
Saint Francis Cancer Center
Clinical Trials Howland Crosswell is currently running
Chemotherapy
for Cancer
This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.
Recruiting
2 awards
Phase 3
26 criteria
Levocarnitine
for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma
This phase III trial compares the effect of adding levocarnitine to standard chemotherapy versus (vs.) standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.
Recruiting
2 awards
Phase 3
More about Howland Crosswell
Clinical Trial Related
6 years of experience running clinical trials · Led 17 trials as a Principal Investigator · 8 Active Clinical Trials
Treatments Howland Crosswell has experience with
- Cyclophosphamide
- Brentuximab Vedotin
- Vincristine Sulfate
- Nivolumab
- Doxorubicin Hydrochloride
- Rituximab
Breakdown of trials Howland Crosswell has run
Hodgkin's Lymphoma
Leukemia
Cancer
Lymphoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Howland Crosswell specialize in?
Howland Crosswell focuses on Hodgkin's Lymphoma and Leukemia. In particular, much of their work with Hodgkin's Lymphoma has involved Stage IV patients, or patients who are Stage III.
Is Howland Crosswell currently recruiting for clinical trials?
Yes, Howland Crosswell is currently recruiting for 8 clinical trials in Greenville South Carolina. If you're interested in participating, you should apply.
Are there any treatments that Howland Crosswell has studied deeply?
Yes, Howland Crosswell has studied treatments such as Cyclophosphamide, Brentuximab Vedotin, Vincristine Sulfate.
What is the best way to schedule an appointment with Howland Crosswell?
Apply for one of the trials that Howland Crosswell is conducting.
What is the office address of Howland Crosswell?
The office of Howland Crosswell is located at: Saint Francis Cancer Center, Greenville, South Carolina 29607 United States. This is the address for their practice at the Saint Francis Cancer Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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