Dr. Deborah W. Wilbur
Claim this profileOncology Associates at Mercy Medical Center
Expert in Breast Cancer
Expert in Breast cancer
78 reported clinical trials
151 drugs studied
Area of expertise
1Breast Cancer
Global LeaderStage IV
Stage III
Stage II
2Breast Cancer
Global LeaderHER2 positive
Stage IV
ER negative
Affiliated Hospitals
Clinical Trials Deborah W. Wilbur is currently running
Chemotherapy + Immunotherapy
for Esophageal and Gastric Cancer
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
Chemotherapy + Hormone Therapy
for Breast Cancer
This trial is testing if adding additional cancer-fighting drugs to treatments that stop certain body functions is better than just using the treatments that stop those functions alone. It targets younger women with early-stage breast cancer who have a higher risk of dying from the disease. The treatment works by stopping certain body functions and using drugs to kill cancer cells.
Recruiting2 awards Phase 319 criteria
More about Deborah W. Wilbur
Clinical Trial Related2 years of experience running clinical trials · Led 78 trials as a Principal Investigator · 44 Active Clinical TrialsTreatments Deborah W. Wilbur has experience with
- Pembrolizumab
- Carboplatin
- Paclitaxel
- Biospecimen Collection
- Nivolumab
- Docetaxel
Breakdown of trials Deborah W. Wilbur has run
Breast Cancer
Breast cancer
Lung Cancer
Esophageal Cancer
Non-Small Cell Lung Cancer
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