Dr. Ardaman Shergill, MD
Claim this profileUniversity of Chicago Comprehensive Cancer Center
Studies Cervical Adenocarcinoma
Studies Colorectal Cancer
25 reported clinical trials
63 drugs studied
Area of expertise
1Cervical Adenocarcinoma
Stage IV
Stage III
HER2 positive
2Colorectal Cancer
Stage IV
Stage III
BRAF negative
Affiliated Hospitals
Clinical Trials Ardaman Shergill, MD is currently running
Chemotherapy + Immunotherapy
for Esophageal and Gastric Cancer
This phase III trial compares the effect of modified fluorouracil, leucovorin calcium, oxaliplatin, and irinotecan (mFOLFIRINOX) to modified fluorouracil, leucovorin calcium, and oxaliplatin (mFOLFOX) for the treatment of advanced, unresectable, or metastatic HER2 negative esophageal, gastroesophageal junction, and gastric adenocarcinoma. The usual approach for patients is treatment with FOLFOX chemotherapy. Chemotherapy drugs work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Fluorouracil stops cells from making DNA and it may kill tumor cells. Leucovorin is used with fluorouracil to enhance the effects of the drug. Oxaliplatin works by killing, stopping, or slowing the growth of tumor cells. Some patients also receive an immunotherapy drug, nivolumab, in addition to FOLFOX chemotherapy. Immunotherapy may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Irinotecan blocks certain enzymes needed for cell division and DNA repair, and it may kill tumor cells. Adding irinotecan to the FOLFOX regimen could shrink the cancer and extend the life of patients with advanced gastroesophageal cancers.
Recruiting2 awards Phase 32 criteria
Atezolizumab + Chemotherapy
for Neuroendocrine Carcinoma
This trial is testing a new treatment combining an immune-boosting drug with standard chemotherapy for patients with a specific type of aggressive cancer that has spread. The goal is to help the immune system fight the cancer and use chemotherapy to kill cancer cells.
Recruiting1 award Phase 2 & 310 criteria
More about Ardaman Shergill, MD
Clinical Trial Related2 years of experience running clinical trials · Led 25 trials as a Principal Investigator · 12 Active Clinical TrialsTreatments Ardaman Shergill, MD has experience with
- Cisplatin
- Irinotecan
- Fluorouracil
- Cetuximab
- Atezolizumab
- Oxaliplatin
Breakdown of trials Ardaman Shergill, MD has run
Cervical Adenocarcinoma
Colorectal Cancer
Cancer
Parotid Gland Cancer
Colon Cancer
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