Dr. Angel E. Torano
Claim this profileAnne Arundel Medical Center
Affiliated Hospitals
Anne Arundel Medical Center
Luminis Health Anne Arundel Medical Center
Clinical Trials Angel E. Torano is currently running
Stereotactic Radiosurgery vs Whole-Brain Radiotherapy
for Brain Metastasis from Lung Cancer
This phase III trial compares the effect of stereotactic radiosurgery to standard of care memantine and whole brain radiation therapy that avoids the hippocampus (the memory zone of the brain) for the treatment of small cell lung cancer that has spread to the brain. Stereotactic radiosurgery is a specialized radiation therapy that delivers a single, high dose of radiation directly to the tumor and may cause less damage to normal tissue. Whole brain radiation therapy delivers a low dose of radiation to the entire brain including the normal brain tissue. Hippocampal avoidance during whole-brain radiation therapy (HA-WBRT) decreases the amount of radiation that is delivered to the hippocampus which is a brain structure that is important for memory. The drug, memantine, is also often given with whole brain radiotherapy because it may decrease the risk of side effects related to thinking and memory. Stereotactic radiosurgery may decrease side effects related to memory and thinking compared to standard of care HA-WBRT plus memantine.
Recruiting
2 awards
Phase 3
15 criteria
Hormone Therapy + Radiation
for Prostate Cancer
This phase III trial uses the Decipher risk score to guide therapy selection. Decipher score is based on the activity of 22 genes in prostate tumor and may predict how likely it is for recurrent prostate cancer to spread (metastasize) to other parts of the body. Decipher score in this study is used for patient selection and the two variations of treatment to be studied: intensification for higher Decipher score or de-intensification for low Decipher score. Patients with higher Decipher risk score will be assigned to the part of the study that compares the use of 6 months of the usual treatment (hormone therapy and radiation treatment) to the use of darolutamide plus the usual treatment (intensification). The purpose of this section of the study is to determine whether the additional drug can reduce the chance of cancer coming back and spreading in patients with higher Decipher score. The addition of darolutamide to the usual treatment may better control the cancer and prevent it from spreading. Alternatively, patients with low Decipher risk score will be assigned to the part of the study that compares the use of radiation treatment alone (de-intensification) to the usual approach (6 months of hormone therapy plus radiation). The purpose of this part of the study is to determine if radiation treatment alone is as effective compared to the usual treatment without affecting the chance of tumor coming back in patients with low Decipher score prostate cancer. Radiation therapy uses high energy to kill tumor cells and reduce the tumor size. Hormone therapy drugs such as darolutamide suppress or block the production or action of male hormones that play role in prostate cancer development. Effect of radiation treatment alone in patients with low Decipher score prostate cancer could be the same as the usual approach in stabilizing prostate cancer and preventing it from spreading, while avoiding the side effects associated with hormonal therapy.
Recruiting
2 awards
Phase 3
1 criteria
More about Angel E. Torano
Clinical Trial Related
4 years of experience running clinical trials · Led 3 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Angel E. Torano has experience with
- Memantine Hydrochloride
- Stereotactic Radiosurgery
- Whole-Brain Radiotherapy
- Bicalutamide
- Buserelin
- Darolutamide
Breakdown of trials Angel E. Torano has run
Brain Metastasis
Brain Tumor
Lung Cancer
Small Cell Lung Cancer
Prostate Adenocarcinoma
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Angel E. Torano specialize in?
Angel E. Torano focuses on Brain Metastasis and Brain Tumor. In particular, much of their work with Brain Metastasis has involved Stage IV patients, or patients who are undergoing treatment.
Is Angel E. Torano currently recruiting for clinical trials?
Yes, Angel E. Torano is currently recruiting for 2 clinical trials in Annapolis Maryland. If you're interested in participating, you should apply.
Are there any treatments that Angel E. Torano has studied deeply?
Yes, Angel E. Torano has studied treatments such as Memantine Hydrochloride, Stereotactic Radiosurgery, Whole-Brain Radiotherapy.
What is the best way to schedule an appointment with Angel E. Torano?
Apply for one of the trials that Angel E. Torano is conducting.
What is the office address of Angel E. Torano?
The office of Angel E. Torano is located at: Anne Arundel Medical Center, Annapolis, Maryland 21401 United States. This is the address for their practice at the Anne Arundel Medical Center.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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