Dr. Amir Khoshbin, MD
Claim this profileSt. Michael's Hospital
Studies Distal Femoral Fractures
Studies Distal Femur Fracture
4 reported clinical trials
7 drugs studied
Affiliated Hospitals
Clinical Trials Amir Khoshbin, MD is currently running
Replacement vs Fixation
for Distal Femur Fractures
Periprosthetic distal femur fractures are a significant source of morbidity and mortality for elderly patients. One treatment option involved a surgical fixation with plates or nails, screws and cables/wires along the side of your fractured bone. The second method consists in replacing your knee joint with an artificial knee prosthesis (artificial knee joint). The primary objective is to determine if acute distal femur replacement improves knee pain and functional outcomes compared to surgical fixation. Secondary outcomes are mortality, reoperation, complications, post-operative pain and quality of life. A health economic analysis will be conducted to assess the cost-effectiveness of both treatments. A total of 148 patients (74/group) will be enrolled in the study.
Recruiting1 award N/A7 criteria
Replacement vs Fixation Surgery
for Distal Femur Fracture
The current standard of care for most intra-articular distal femur fractures (above the knee joint) in geriatric patients is a surgical fixation using plates and screws to hold the fracture pieces in the correct position, until the fracture as healed. However, surgical fixation of these complex fractures in geriatric patients, is associated with significant complications, such as non-union (when the broken bone does not heal properly), infection and the need for revision surgery. Additionally, surgical fixation requires prolonged immobilization of of the affected limb (typically around 6-12 weeks post-operatively), which can lead to disability and other complications. Geriatric patients, especially those frail and with cognition impairment, are unable to adhere to the immobilization restrictions, which leads to an increased risk of fixation failure (broken bone does not heal). Another treatment option for those patients is an acute distal femoral replacement (artificial knee), where damaged parts of the knee joint are replaced with artificial prosthesis. This procedure allows patients to walk immediately after the surgery and faster return to previous level of function, therefore avoiding the complications for immobilization. There is a lack of guideline and evidence to suggest which surgical technique is best to provide superior function outcomes, lower complications and reduced costs. The proposed study seeks to answer this question by performing a large clinical trial comparing knee replacement versus surgical fixation in geriatric patients with distal femur fracture.
Recruiting1 award N/A9 criteria
More about Amir Khoshbin, MD
Clinical Trial Related1 year of experience running clinical trials · Led 4 trials as a Principal Investigator · 2 Active Clinical TrialsTreatments Amir Khoshbin, MD has experience with
- Distal Femoral Replacement
- Surgical Fixation (ORIF)
- Simultaneous Knee Arthroplasty (UKA)
- Staged Knee Arthroplasty (UKA)
- OR3O™ Dual Mobility System
- Distal Femur Replacement
Breakdown of trials Amir Khoshbin, MD has run
Distal Femoral Fractures
Distal Femur Fracture
Hip osteoarthritis
Hip Revision Surgery
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Frequently asked questions
Do I need insurance to participate in a trial?
Almost all clinical trials will cover the cost of the ‘trial drug’ — so no insurance is required for this. For trials where this trial drug is given alongside an already-approved medication, there may be a cost (which your insurance would normally cover).
What does Amir Khoshbin, MD specialize in?
Amir Khoshbin, MD focuses on Distal Femoral Fractures and Distal Femur Fracture. In particular, much of their work with Distal Femoral Fractures has involved treating patients, or patients who are undergoing treatment.
Is Amir Khoshbin, MD currently recruiting for clinical trials?
Yes, Amir Khoshbin, MD is currently recruiting for 2 clinical trials in Toronto Ontario. If you're interested in participating, you should apply.
Are there any treatments that Amir Khoshbin, MD has studied deeply?
Yes, Amir Khoshbin, MD has studied treatments such as Distal femoral replacement, Surgical Fixation (ORIF), Simultaneous Knee Arthroplasty (UKA).
What is the best way to schedule an appointment with Amir Khoshbin, MD?
Apply for one of the trials that Amir Khoshbin, MD is conducting.
What is the office address of Amir Khoshbin, MD?
The office of Amir Khoshbin, MD is located at: St. Michael's Hospital, Toronto, Ontario M5B 1W8 Canada. This is the address for their practice at the St. Michael's Hospital.
Is there any support for travel costs?
The coverage of travel expenses can vary greatly between different clinical trials. Please see more financial detail in the trials you’re interested to apply.
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