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Staged vs Simultaneous Knee Replacement for Osteoarthritis

N/A

Waitlist Available

Led By Eric R. Bohm, MD

Research Sponsored by Orthopaedic Innovation Centre

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Patients considering bilateral knee arthroplasty

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 1 year

Awards & highlights

Study Summary

This trial will help answer the question of whether it is better to have both knees replaced at the same time or to do one and wait to do the second one.

Who is the study for?

This trial is for individuals considering bilateral knee arthroplasty, who are able to sign a consent form and willing to complete study questionnaires. It's not suitable for those unable to fill out the questionnaires or who need simultaneous surgery due to severe knee contractures.Check my eligibility

What is being tested?

The study aims to determine whether it's better for patients with osteoarthritis to have both knees replaced at once (simultaneous) or one at a time (staged). Participants will be assigned one of these two surgical approaches.See study design

What are the potential side effects?

Potential side effects from either surgical approach may include pain, swelling, infection risk, blood clots, stiffness in the knee joint, and complications related to anesthesia.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am considering surgery for both of my knees.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 1 year

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~1 year

This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Veterans Rand 12-item Health Survey Score (VR-12)

Secondary outcome measures

Complications

Costs of knee replacement surgery

Hospital stay

+4 more

Trial Design

2Treatment groups

Active Control

Group I: Unicompartmental Knee Arthroplasty (UKA)Active Control2 Interventions

Patient will have half-knee replacement (partial) - Simultaneous vs Staged

Group II: Total Knee Arthroplasty (TKA)Active Control2 Interventions

Patient will have complete replacement - Simultaneous vs Staged

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

Orthopaedic Innovation CentreLead Sponsor

5 Previous Clinical Trials

421 Total Patients Enrolled

2 Trials studying Osteoarthritis

190 Patients Enrolled for Osteoarthritis

Eric R. Bohm, MDPrincipal InvestigatorUniversity of Manitoba

Media Library

Simultaneous Knee Arthroplasty (UKA) Clinical Trial Eligibility Overview. Trial Name: NCT03564730 — N/A

Osteoarthritis Research Study Groups: Unicompartmental Knee Arthroplasty (UKA), Total Knee Arthroplasty (TKA)

Osteoarthritis Clinical Trial 2023: Simultaneous Knee Arthroplasty (UKA) Highlights & Side Effects. Trial Name: NCT03564730 — N/A

Simultaneous Knee Arthroplasty (UKA) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03564730 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrolment still an option for participants in this research trial?

"According to the information on clinicaltrials.gov, this research is actively seeking participants as of now. The study was initially launched in March 2018 and its details were most recently reviewed during May 2022."

Answered by AI

Is there a broad geographic distribution of this medical trial in North America?

"At present, this medical trial is recruiting from 7 sites situated in cities such as Calgary, Ottawa, and Winnipeg. To minimize travel demands for yourself if you decide to participate, it is recommended to select the site closest to your location."

Answered by AI

How many participants are included in the current clinical trial?

"Affirmative, the data hosted on clinicaltrials.gov reveals that this research endeavour is currently enrolling individuals. It was initially posted on March 19th 2018 and has been amended as recently as May 16th 2022. 224 volunteers are desired from 7 different trial sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Staged Versus Simultaneous Bilateral Knee Arthroplasty

2018. "Staged Versus Simultaneous Bilateral Knee Arthroplasty". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03564730.