Alfonso Fasano | UHN Research

Dr. Alfonso Fasano, MD, PhD

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Movement Disorders Centre - Toronto Western Hospital

Studies Parkinson's Disease
Studies Essential Tremor
5 reported clinical trials
8 drugs studied

Affiliated Hospitals

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Movement Disorders Centre, Toronto Western Hospital

Clinical Trials Alfonso Fasano, MD, PhD is currently running

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DBS Programming

for Essential Tremor

Population Size and Eligible Patients: The investigators aim to recruit 5 to 10 patients with tremors who have previously undergone Ventral Intermedius Deep Brain Stimulation (VIM-DBS) treatment but have experienced early or late loss of benefits. Additionally, the investigators will enroll ten patients with essential tremor who require VIM-DBS surgery. These individuals will undergo bilateral implantation of Boston Scientific Genus Implantable Pulse Generator (IPG) devices, connected to Boston Scientific Cartesia™ 8-contact Directional Leads. Study Design: This study comprises two distinct phases. Phase 1 is a cross-sectional investigation designed to identify the optimal algorithm for patterned stimulation in the VIM region . Phase 2 is a prospective clinical trial focusing on the assessment of safety and efficacy of bilateral VIM-DBS in patients with essential tremor. Objectives: The primary objective in Phase 2 is to evaluate the safety and effectiveness of bilateral VIM-DBS in individuals with essential tremor. In Phase 1, the investigators seek to explore the impact of the Chronos programming software on tremor patients who have experienced early or late loss of benefits.
Recruiting1 award N/A
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Deep Brain Stimulation

for Parkinson's Disease

This trial tests a new type of brain stimulation for Parkinson's patients that adjusts itself automatically based on brain activity. It aims to help those who have symptoms like freezing of gait or trouble speaking, which are not well-treated by current methods. This new approach has been shown to be at least as effective as traditional methods, with reduced stimulation time and fewer side effects.
Recruiting1 award N/A7 criteria

More about Alfonso Fasano, MD, PhD

Clinical Trial Related2 years of experience running clinical trials · Led 5 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Alfonso Fasano, MD, PhD has experience with
  • Deep Brain Stimulation
  • Physiotherapy
  • Programming DBS Using Percept PC Neurostimulator's Full Potential
  • Standard Of Care Programming
  • Directional Bilateral Thalamic Patterned Stimulation
  • DBS Virtual Learning Experience

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