WEILL, Alain | CHUM

Dr. Alain Weill, MD

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Centre Hospitalier de l'Université de Montréal

Studies Intracranial Aneurysms
Studies Superior Mesenteric Artery Aneurysm
7 reported clinical trials
11 drugs studied

Affiliated Hospitals

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Centre Hospitalier De L'Université De Montréal
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Centre Hospitalier De L'Université De Montréal - Hôpital Notre Dame

Clinical Trials Alain Weill, MD is currently running

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Endovascular Repair Techniques

for Brain Aneurysm

Intracranial bifurcation aneurysms are commonly repaired with surgical and with endovascular techniques. Wide-necked bifurcation aneurysms (WNBA) are a difficult subset of aneurysms to successfully repair endovascularly, and a number of treatment adjuncts have been designed. One particularly promising innovation is the WEB (Woven EndoBridge), which permits placement of an intra-saccular flow diverting mesh across the aneurysm neck, but which does not require anti-platelet agent therapy. Currently, which treatment option leads to the best outcome for patients with WNBA remains unknown. There is a need to offer treatment with the WEB within the context of a randomized care trial, to patients currently presenting with aneurysms thought to be suitable for the WEB.
Recruiting1 award N/A5 criteria
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Multimodal Therapy

for Brain AVM

The objectives of this study and registry are to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of uncertainty. Management may include interventional therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in combination) or conservative management. The trial has been designed to test a) whether medical management or interventional therapy will reduce the risk of death or debilitating stroke (due to hemorrhage or infarction) by an absolute magnitude of about 15% (over 10 years) for unruptured AVMs (from 30% to 15%); and, b) to test if endovascular treatment can improve the safety and efficacy of surgery or radiation therapy by at least 10% (80% to 90%). As for the nested trial on the role of embolization in the treatment of Brain AVMs by other means: the pre-surgical or pre-radiosurgery embolization of cerebral AVMs can decrease the number of treatment failures from 20% to 10%. In addition,embolization of cerebral AVMs can be accomplished with an acceptable risk, defined as permanent disabling neurological complications of 8%.
Recruiting1 award N/A1 criteria

More about Alain Weill, MD

Clinical Trial Related14 years of experience running clinical trials · Led 7 trials as a Principal Investigator · 2 Active Clinical Trials
Treatments Alain Weill, MD has experience with
  • Endovascular Management
  • Surgical Management
  • Embolization
  • Neurosurgery
  • Radiation Therapy
  • Endovascular Coiling

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