Pulmonary Hypertension Clinical Trials
Here are the 6 most popular medical studies for pulmonary hypertension
Biguanide
Metformin for Pulmonary Hypertension
This trial is testing whether the diabetes drug metformin can improve outcomes in people with PH-HFpEF. The study will look at how well metformin works compared to placebo and what the effects are on heart function and capacity.
Popular filter options for pulmonary hypertension trials
PH Clinical Trials
View 41 PH medical studies.
Soluble Guanylate Cyclase Stimulator
MK-5475 for Pulmonary Arterial Hypertension
This trial is testing a new drug, MK-5475, to see if it can help people with pulmonary arterial hypertension. There will be two parts to the trial. In the first part, different doses of the drug will be tested against a placebo to see if there are any benefits. The second part of the trial will be a longer study to confirm the results of the first part.
Prostacyclin Receptor Agonist
Ralinepag for Pulmonary Arterial Hypertension
This trial is for participants with pulmonary arterial hypertension who have participated in another study of ralinepag. It is an extension study, which means participants will continue to receive the study drug.
Pulmonary Arterial Hypertension Clinical Trials
View 38 Pulmonary Arterial Hypertension medical studies.
Soluble Guanylate Cyclase Stimulator
MK-5475 for Pulmonary Arterial Hypertension
This trial is testing a new drug, MK-5475, to see if it can help people with pulmonary arterial hypertension. There will be two parts to the trial. In the first part, different doses of the drug will be tested against a placebo to see if there are any benefits. The second part of the trial will be a longer study to confirm the results of the first part.
Prostacyclin Receptor Agonist
Ralinepag for Pulmonary Arterial Hypertension
This trial is for participants with pulmonary arterial hypertension who have participated in another study of ralinepag. It is an extension study, which means participants will continue to receive the study drug.
Procedure
TIVUSâ„¢ System for Pulmonary Hypertension
This trial will study the safety and effectiveness of the TIVUSâ„¢ System for treating pulmonary artery hypertension. Up to 15 patients will be enrolled in this prospective, open-label study at 4 centers.
Phase 3 Pulmonary Hypertension Clinical Trials
View 78 phase 3 pulmonary hypertension medical studies.
Soluble Guanylate Cyclase Stimulator
MK-5475 for Pulmonary Arterial Hypertension
This trial is testing a new drug, MK-5475, to see if it can help people with pulmonary arterial hypertension. There will be two parts to the trial. In the first part, different doses of the drug will be tested against a placebo to see if there are any benefits. The second part of the trial will be a longer study to confirm the results of the first part.
Prostacyclin Receptor Agonist
Ralinepag for Pulmonary Arterial Hypertension
This trial is for participants with pulmonary arterial hypertension who have participated in another study of ralinepag. It is an extension study, which means participants will continue to receive the study drug.
Angiogenic Cell Therapy
Angiogenic Cell Therapy for Pulmonary Hypertension
This trial is testing whether a treatment involving a person's own cells, transfected with human eNOS, is effective and safe for patients with severe PAH who are already on other PAH-targeted therapies.
Pulmonary Hypertension Clinical Trials With No Placebo
View 78 pulmonary hypertension medical studies that do not have a placebo group.
Computerized Decision Support for Pulmonary Hypertension
This trial will test whether or not an electronic health record alert will increase echocardiographic screening for CTEPH and the diagnosis of CTEPH in patients with prior pulmonary embolism and symptoms/signs suggestive of pulmonary hypertension or recent pulmonary testing suggesting unexplained respiratory symptoms.
Prostacyclin Receptor Agonist
Ralinepag for Pulmonary Arterial Hypertension
This trial is for participants with pulmonary arterial hypertension who have participated in another study of ralinepag. It is an extension study, which means participants will continue to receive the study drug.
Procedure
TIVUSâ„¢ System for Pulmonary Hypertension
This trial will study the safety and effectiveness of the TIVUSâ„¢ System for treating pulmonary artery hypertension. Up to 15 patients will be enrolled in this prospective, open-label study at 4 centers.
View More Pulmonary Hypertension Trials
See another 56 medical studies focused on pulmonary hypertension.
Frequently Asked Questions
Introduction to pulmonary hypertension
What are the top hospitals conducting pulmonary hypertension research?
When it comes to the complex and often misunderstood condition of pulmonary hypertension, several hospitals are leading the way in cutting-edge clinical trials. In Boston, Massachusetts General Hospital stands out with four active trials dedicated to this challenging disease, along with a remarkable track record of 28 completed studies. Since initiating their first trial in 2002, they have been at the forefront of research and innovation for pulmonary hypertension treatment. Meanwhile, on the East Coast in Baltimore, the University of Maryland Medical Center has also made significant contributions with three ongoing trials and seven previously conducted ones since their debut study in 2012.
Traveling down south to Gainesville, Florida, we find that the University of Florida is making strides as well; currently conducting three active clinical trials focused on pulmonary hypertension while having successfully completed nine previous investigations since their inaugural trial began in 2006. Not far from there is Tufts Medical Center in Boston where researchers are actively engaged in three pivotal pulmonary hypertension clinical trials alongside completing twenty-seven other important research projects on this subject after starting off back almost two decades ago duringthe year2005.
Lastly but certainly not leastly,the University of Colorado Hospital locatedin Aurora continuescontributingto our understandingofpulmonaryhypertensionwiththreeactiveclinicaltrials.The noteworthy aspect hereis thatalthoughtherehaveonlybeenthreecompletedtrialssincetheirfirstinvestigationwasinitiatedin2017,thisinstitutionhas managedtomakea significantsplashinthefieldanddemonstratetheirexpertiseanddedicationtowardsthisseverelyunderdiagnosedcondition
As these top hospitals continue to push boundaries and explore new avenues for treating pulmonary hypertension patients worldwide can take comfort knowing that dedicated experts are tirelessly working towards improved outcomes and breakthroughs for this debilitating condition
Which are the best cities for pulmonary hypertension clinical trials?
When it comes to pulmonary hypertension clinical trials, several cities excel in conducting cutting-edge research. Los Angeles, California; Boston, Massachusetts; Indianapolis, Indiana; Houston, Texas; and Philadelphia, Pennsylvania are among the top cities with active trials. These studies focus on a range of experimental treatments such as Ralinepag, Sotatercept 0.3 mg/kg (escalating to 0.7 mg/kg), Macitentan, MK-5475, Selexipag, and Long Term Follow Up protocols. With their extensive involvement in ongoing research efforts for pulmonary hypertension treatment options, these cities offer individuals affected by this condition access to promising clinical trials that may lead to improved care outcomes.
Which are the top treatments for pulmonary hypertension being explored in clinical trials?
Pulmonary hypertension research is advancing, with a focus on exploring effective treatments in clinical trials. Leading the way is Ralinepag, currently being tested in two active trials for pulmonary hypertension. Since its introduction in 2018, it has been involved in three all-time clinical trials dedicated to this condition. Another promising contender is MK-5475, which recently made its debut and already has one ongoing trial for pulmonary hypertension among its three all-time trials. These innovative treatments hold promise for improving the lives of patients battling this challenging disease.
What are the most recent clinical trials for pulmonary hypertension?
Recent clinical trials offer hope for individuals with pulmonary hypertension, a condition characterized by high blood pressure in the arteries of the lungs. Among these trials is Hyperpolarized 129Xe, which has entered Phase 2 and shows promise as a potential treatment option. Additionally, AZD3427 Dose A and Treprostinil Palmitil have also progressed to Phase 2, providing further opportunities for advancing therapeutic interventions. These studies aim to improve our understanding and management of pulmonary hypertension, ultimately enhancing patient outcomes and quality of life.
What pulmonary hypertension clinical trials were recently completed?
Several notable clinical trials focusing on pulmonary hypertension have recently concluded, shedding light on potential advancements in the treatment of this condition. Actelion's trial for Selexipag reached completion in February 2021, offering insights into its effectiveness. Additionally, the University of Washington successfully completed a trial exploring the use of Famotidine 20 MG in May 2019. In January 2019, Northwell Health completed their investigation into Alteplase as a potential therapy for pulmonary hypertension. These recent trials contribute to our understanding and pave the way for further breakthroughs in combatting this challenging disease.