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Charlottesville

University of Virginia Health System

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Charlottesville, Virginia 22901

Global Leader in Lung Cancer

Global Leader in Cancer

Conducts research for Coronary Artery Disease

Conducts research for Ovarian Cancer

Conducts research for Stroke

398 reported clinical trials

52 medical researchers

Photo of University of Virginia Health System in CharlottesvillePhoto of University of Virginia Health System in CharlottesvillePhoto of University of Virginia Health System in Charlottesville

Summary

University of Virginia Health System is a medical facility located in Charlottesville, Virginia. This center is recognized for care of Lung Cancer, Cancer, Coronary Artery Disease, Ovarian Cancer, Stroke and other specialties. University of Virginia Health System is involved with conducting 398 clinical trials across 567 conditions. There are 52 research doctors associated with this hospital, such as Linda Duska, MD, Scott Lim, MD, Richard D. Hall, and Matthew J. Reilley.

Area of expertise

1

Lung Cancer

Global Leader

University of Virginia Health System has run 26 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive
2

Cancer

Global Leader

University of Virginia Health System has run 25 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
ARID1A positive

Top PIs

Clinical Trials running at University of Virginia Health System

Cancer

Lung Cancer

Stroke

Heart Failure

Prostate Cancer

Ovarian Cancer

Atrial Fibrillation

Small Cell Lung Cancer

Breast Cancer

Non-Small Cell Lung Cancer

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Mirvetuximab + Bevacizumab

for Ovarian Cancer

GLORIOSA is a Phase 3 multicenter, open label study designed to evaluate the safety and efficacy of mirvetuximab Soravtansine + Bevacizumab as maintenance therapy in participants with platinum-sensitive ovarian, primary peritoneal or fallopian tube cancers with high folate receptor-alpha (FRα) expression.

Recruiting

2 awards

Phase 3

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Pembrolizumab

for Advanced Cancers

The purpose of this study is to evaluate the long-term safety and efficacy of pembrolizumab (MK-3475) in participants from previous Merck pembrolizumab-based parent studies who transition into this extension study. This study will consist of three phases: 1) First Course Phase, 2) Survival Follow-up Phase or 3) Second Course Phase. Each participant will transition to this extension study in one of the following three phases, depending on the study phase they were in at the completion of the parent study. Participants who were in the First Course Phase of study treatment with pembrolizumab or lenvatinib in their parent study will enter the First Course Phase of this study and complete up to 35 doses or more every 3 weeks (Q3W) or 17 doses or more every 6 weeks (Q6W) of study treatment with pembrolizumab or a pembrolizumab-based combination or lenvatinib according to arm assignment. Participants who were in the Follow-up Phase in the parent study (post-treatment or Survival Follow-up Phase) will enter the Survival Follow-up Phase of this study. Participants who were in the Second Course Phase in their parent study will enter Second Course Phase of this study and complete up to 17 doses Q3W or 8 doses Q6W of study treatment with pembrolizumab or a pembrolizumab-based combination according to arm assignment. Any participant originating from a parent trial where crossover to pembrolizumab was permitted upon disease progression may be eligible for 35 doses as Q3W or 17 doses Q6W of pembrolizumab (approximately 2 years), if they progress while on the control arm and pembrolizumab is approved for the indication in the country where the potential eligible crossover participant is being evaluated.

Recruiting

2 awards

Phase 3

4 criteria

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LY3537982 + Immunotherapy/Chemotherapy

for Non-Small Cell Lung Cancer

This trial is testing a new drug, LY3537982, combined with standard treatments for patients with advanced lung cancer that have a specific genetic mutation. The goal is to see if this combination works better than the usual treatments alone.

Recruiting

1 award

Phase 3

14 criteria

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