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University of Virginia

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Charlottesville, Virginia 22902
Global Leader in Type 1 Diabetes
Global Leader in Breast Cancer
Conducts research for Heart Failure
Conducts research for Cancer
Conducts research for Lung Cancer
917 reported clinical trials
137 medical researchers
Photo of University of Virginia in CharlottesvillePhoto of University of Virginia in Charlottesville

Summary

University of Virginia is a medical facility located in Charlottesville, Virginia. This center is recognized for care of Type 1 Diabetes, Breast Cancer, Heart Failure, Cancer, Lung Cancer and other specialties. University of Virginia is involved with conducting 917 clinical trials across 1,250 conditions. There are 137 research doctors associated with this hospital, such as Linda Duska, MD, Scott Lim, MD, Richard D. Hall, and Matthew J. Reilley.

Area of expertise

1Type 1 Diabetes
Global Leader
University of Virginia has run 47 trials for Type 1 Diabetes. Some of their research focus areas include:
GAD65
IA-2
ZnT8
2Breast Cancer
Global Leader
University of Virginia has run 34 trials for Breast Cancer. Some of their research focus areas include:
Stage III
HER2 negative
Stage IV

Top PIs

Clinical Trials running at University of Virginia

Breast Cancer
Lung Cancer
Heart Failure
Melanoma
Ovarian Cancer
Cancer
Cervical Cancer
Asthma
Lymphoma
Eosinophilic Esophagitis
Image of trial facility.

Chemoradiation

for High-risk Breast Cancer

The goal of this study is to evaluate the safety and effectiveness of adjuvant chemoradiation therapy in high-risk breast cancer patients who had received neoadjuvant chemotherapy before their lumpectomy and/or mastectomy and were found to have residual disease. As well as examine the effects of this treatment combination on the immune system.
Recruiting3 awards Phase 2 & 314 criteria
Image of trial facility.

Sacituzumab Govitecan + Pembrolizumab

for Triple Negative Breast Cancer

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after surgery and pre-surgical treatment.
Recruiting2 awards Phase 36 criteria
Image of trial facility.

Tranexamic Acid

for Breast Reconstruction

Tranexamic acid (TXA) is a synthetic, competitive lysine receptor inhibitor on plasminogen. It ultimately stabilizes the fibrin matrix, therefore used as a hemostatic agent for various indications. While there has been indications for orthopedic and trauma surgery, there is no clear data for its role in patients who are undergoing free tissue transfer. Studies have shown that patients undergoing free tissue transfer can have transfusion rates ranging from 7.2% to 34.9%, which data also showing association between transfusion requirement and higher free flap failure rate. There has been a few retrospective studies that evaluated the effect of TXA in free tissue transfer and the results showed no increased risk of microanastomosis failure but some showing decreased blood loss. This study aims to further analyze the role of TXA in patients undergoing breast free flap reconstruction with randomized, prospective trial. Control group will not receive TXA while experimental group will receive TXA. Both groups will receive standard of care breast free flap surgery as well as post-op care, which is streamlined with Early Recovery After Surgery (ERAS) protocol. Their pre and post-op hemoglobin will be compared, as well as rates of transfusion, surgical outcome and surgical complications including hematoma, flap failure, and any other medical complications such as Deep Vein Thrombosis (DVT)/ Pulmonary Embolism (PE).
Recruiting2 awards Phase 41 criteria

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Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Terms of Service·Privacy Policy·Cookies·Security