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University of Michigan Comprehensive Cancer Center

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Ann Arbor, Michigan 48109

Global Leader in Breast Cancer

Global Leader in Cancer

Conducts research for Lung Cancer

Conducts research for Prostate Cancer

Conducts research for Pancreatic Cancer

856 reported clinical trials

60 medical researchers

Photo of University of Michigan Comprehensive Cancer Center in Ann ArborPhoto of University of Michigan Comprehensive Cancer Center in Ann ArborPhoto of University of Michigan Comprehensive Cancer Center in Ann Arbor

Summary

University of Michigan Comprehensive Cancer Center is a medical facility located in Ann Arbor, Michigan. This center is recognized for care of Breast Cancer, Cancer, Lung Cancer, Prostate Cancer, Pancreatic Cancer and other specialties. University of Michigan Comprehensive Cancer Center is involved with conducting 856 clinical trials across 636 conditions. There are 60 research doctors associated with this hospital, such as Paul Swiecicki, Rashmi Chugh, MD, Vaibhav Sahai, MBBS, MS, and Francis P. Worden.

Area of expertise

1

Breast Cancer

Global Leader

University of Michigan Comprehensive Cancer Center has run 108 trials for Breast Cancer. Some of their research focus areas include:

HER2 negative
ER positive
Stage IV
2

Cancer

Global Leader

University of Michigan Comprehensive Cancer Center has run 90 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage I

Top PIs

Clinical Trials running at University of Michigan Comprehensive Cancer Center

Breast Cancer

Cancer

Skin Cancer

Breast cancer

Kidney Cancer

Prostate Cancer

Lung Cancer

Pancreatic Cancer

Ovarian Cancer

Testicular cancer

Image of trial facility.

Carvedilol

for Preventing Heart Problems in HER2 Positive Breast Cancer

This trial has two cohorts of patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. All patients must be receiving trastuzumab-based treatment. Both cohorts are being observed for cardiac toxicity. The largest cohort (currently open to accrual) is observational, and contains patients who are taking a beta blocker, ACE inhibitor, or ARB as well as their trastuzumab-based treatment. The goal is to understand how common cardiac problems are in this group of patients at high risk. The smaller cohort (currently closed to accrual) is randomized. Patients in this second cohort are randomized to either carvedilol or no treatment, with the goal of seeing whether carvedilol (used to treat heart failure and high blood pressure) may prevent the heart from side effects of chemotherapy.

Recruiting

2 awards

Phase 3

23 criteria

Image of trial facility.

Radiation Therapy

for Brain Metastasis

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the brain. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. FSRS delivers a high dose of radiation to the tumor over 3 treatments. SRS is a type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor. FSRS may be more effective compared to SRS in treating patients with cancer that has spread to the brain.

Recruiting

2 awards

Phase 3

12 criteria

Image of trial facility.

Low Dose Tamoxifen

for Breast Cancer

This phase III trial compares the effect of low dose tamoxifen to usual hormonal therapy, including aromatase inhibitors, in treating post-menopausal women with hormone positive, HER2 negative early stage breast cancer. Tamoxifen is in a class of medications known as antiestrogens. It blocks the activity of estrogen (a female hormone) in the breast. This may stop the growth of some breast tumors that need estrogen to grow. Aromatase inhibitors, such as anastrozole, letrozole, and exemestane, prevent the formation of estradiol, a female hormone, by interfering with an aromatase enzyme. Aromatase inhibitors are used as a type of hormone therapy to treat postmenopausal women with hormone-dependent breast cancer. Giving low dose tamoxifen may be more effective compared to usual hormone therapy in treating post-menopausal women with hormone-positive, HER2 negative early stage breast cancer.

Recruiting

2 awards

Phase 3

8 criteria

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