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University of Miami Miller School of Medicine-Sylvester Cancer Center

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Miami, Florida 33136

Global Leader in Cancer

Global Leader in Lung Cancer

Conducts research for Breast Cancer

Conducts research for Brain Tumor

Conducts research for Lymphoma

793 reported clinical trials

85 medical researchers

Photo of University of Miami Miller School of Medicine-Sylvester Cancer Center in MiamiPhoto of University of Miami Miller School of Medicine-Sylvester Cancer Center in MiamiPhoto of University of Miami Miller School of Medicine-Sylvester Cancer Center in Miami

Summary

University of Miami Miller School of Medicine-Sylvester Cancer Center is a medical facility located in Miami, Florida. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Brain Tumor, Lymphoma and other specialties. University of Miami Miller School of Medicine-Sylvester Cancer Center is involved with conducting 793 clinical trials across 813 conditions. There are 85 research doctors associated with this hospital, such as Julio C Barredo, MD, Jose Lutzky, MD, Chukwuemeka (Emeka) V. Ikpeazu, and Macarena I. De La Fuente.

Area of expertise

1

Cancer

Global Leader

University of Miami Miller School of Medicine-Sylvester Cancer Center has run 136 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage I
2

Lung Cancer

Global Leader

University of Miami Miller School of Medicine-Sylvester Cancer Center has run 90 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
Stage II

Top PIs

Clinical Trials running at University of Miami Miller School of Medicine-Sylvester Cancer Center

Cancer

Skin Cancer

Lung Cancer

Prostate Cancer

Brain Tumor

Ovarian Cancer

Breast Cancer

Multiple Myeloma

Cervical Cancer

Pancreatic Cancer

Image of trial facility.

Immunotherapy + Chemotherapy

for Sarcoma

This phase III trial compares the effect of immunotherapy (pembrolizumab) plus chemotherapy (doxorubicin) to chemotherapy (doxorubicin) alone in treating patients with dedifferentiated liposarcoma (DDLPS), undifferentiated pleomorphic sarcoma (UPS) or a related poorly differentiated sarcoma that has spread from where it first started (primary site) to other places in the body (metastatic) or that cannot be removed by surgery (unresectable). Doxorubicin is in a class of medications called anthracyclines. Doxorubicin damages the cell's deoxyribonucleic acid (DNA) and may kill tumor cells. It also blocks a certain enzyme needed for cell division and DNA repair. A monoclonal antibody is a type of protein that can bind to certain targets in the body, such as molecules that cause the body to make an immune response (antigens). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Adding immunotherapy (pembrolizumab) to the standard chemotherapy (doxorubicin) may help patients with metastatic or unresectable DDLPS, UPS or a related poorly differentiated sarcoma live longer without having disease progression.

Recruiting

2 awards

Phase 3

10 criteria

Image of trial facility.

Radiation Therapy

for Brain Metastasis

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the brain. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. FSRS delivers a high dose of radiation to the tumor over 3 treatments. SRS is a type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor. FSRS may be more effective compared to SRS in treating patients with cancer that has spread to the brain.

Recruiting

2 awards

Phase 3

12 criteria

Image of trial facility.

Radiation Therapy

for Cancer with Bone Metastasis

This phase III trial compares the effect of adding radiation therapy to usual care on the occurrence of bone-related complications in cancer patients with high-risk bone metastases that are not causing symptoms (asymptomatic). High-risk bone metastases are defined by their location (including hip, shoulder, long bones, and certain levels of the spine), or size (2 cm or larger). These bone metastases appear to be at higher risk of complications such as fracture, spinal cord compression, and/or pain warranting surgery or radiation treatment. Radiation therapy uses high energy x-rays to kill cancer cells and shrink tumors. The total dose of radiation can be delivered in a single day or divided in smaller doses for up to 5 days of total treatment. Usual care for asymptomatic bone metastases may include drugs that prevent bone loss, in addition to the treatment for the primary cancer or observation (which means no treatment until symptoms appear). Evidence has shown that preventative radiation therapy may be effective in lowering the number of bone metastases-related complications, however, it is not known if this approach is superior to usual care. Adding radiation therapy to usual care may be more effective in preventing bone-related complications than usual care alone in cancer patients with asymptomatic high-risk bone metastases.

Recruiting

2 awards

Phase 3

7 criteria

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