UM Sylvester Comprehensive Cancer Center at Plantation

Summary

UM Sylvester Comprehensive Cancer Center at Plantation is a medical facility located in Fort Lauderdale, Florida. This center is recognized for care of Cancer, Lung Cancer, Breast Cancer, Breast cancer, Pancreatic Cancer and other specialties. UM Sylvester Comprehensive Cancer Center at Plantation is involved with conducting 93 clinical trials across 202 conditions. There are 42 research doctors associated with this hospital, such as Jose Lutzky, MD, Chukwuemeka (Emeka) V. Ikpeazu, Aman Chauhan, MD, and Macarena I. De La Fuente.

Top PIs

Clinical Trials running at UM Sylvester Comprehensive Cancer Center at Plantation

Skin Cancer

Lung Cancer

Prostate Cancer

Breast Cancer

Cancer

Ovarian Cancer

Melanoma

Cutaneous Melanoma

Pancreatic Cancer

Breast cancer

Radiation Therapy

for Brain Metastasis

This phase III trial compares the effectiveness of fractionated stereotactic radiosurgery (FSRS) to usual care stereotactic radiosurgery (SRS) in treating patients with cancer that has spread from where it first started to the brain. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. FSRS delivers a high dose of radiation to the tumor over 3 treatments. SRS is a type of external radiation therapy that uses special equipment to position the patient and precisely give a single large dose of radiation to a tumor. FSRS may be more effective compared to SRS in treating patients with cancer that has spread to the brain.

Recruiting

2 awards

Phase 3

12 criteria

Cemiplimab + Surgery

for Advanced Skin Cancer

This phase III trial compares the effect of adding cemiplimab to standard therapy (surgery with or without radiation) versus standard therapy alone in treating patients with stage III/IV squamous cell skin cancer that is able to be removed by surgery (resectable) and that may have come back after a period of improvement (recurrent). The usual treatment for patients with resectable squamous cell skin cancer is the removal of the cancerous tissue (surgery) with or without radiation, which uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Immunotherapy with monoclonal antibodies, such as cemiplimab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Cemiplimab has been approved for the treatment of skin cancer that has spread or that cannot be removed by surgery, but it has not been approved for the treatment of skin cancer than can be removed by surgery. Adding cemiplimab to the usual treatment of surgery with or without radiation may be more effective in treating patients with stage III/IV resectable squamous cell skin cancer than the usual treatment alone.

Recruiting

2 awards

Phase 3

7 criteria

Biomarker-Guided Immunotherapy Discontinuation

for Melanoma

This trial uses drugs that boost the immune system to fight advanced melanoma that can't be surgically removed. It aims to see if doctors can safely shorten the treatment period by using imaging tests to guide decisions. Pembrolizumab and ipilimumab are immunotherapy drugs used to treat advanced melanoma, with pembrolizumab approved for younger patients and ipilimumab showing positive results in previous studies.

Recruiting

1 award

Phase 2

22 criteria