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Orange County Research Center
Claim this profileTustin, California 92780
Global Leader in Diabetes
Global Leader in Type 2 Diabetes
Conducts research for Liver Disease
Conducts research for Healthy Subjects
Conducts research for High Blood Pressure
140 reported clinical trials
2 medical researchers
Summary
Orange County Research Center is a medical facility located in Tustin, California. This center is recognized for care of Diabetes, Type 2 Diabetes, Liver Disease, Healthy Subjects, High Blood Pressure and other specialties. Orange County Research Center is involved with conducting 140 clinical trials across 84 conditions. There are 2 research doctors associated with this hospital, such as JOEL MICHAEL NEUTEL and Joel M Neutel.Top PIs
JOEL MICHAEL NEUTELOrange County Research Center1 year of reported clinical research
Studies Liver Disease
Studies Fatty Liver Disease
3 reported clinical trials
4 drugs studied
Joel M NeutelOrange County Research Center2 years of reported clinical research
Studies Liver Disease
Studies Fatty Liver Disease
1 reported clinical trial
1 drug studied
Clinical Trials running at Orange County Research Center
Liver Disease
Flu
Kidney Failure
Chronic Hepatitis D
Non-alcoholic Fatty Liver Disease
Obesity
Diabetes
Chronic Kidney Disease
Cardiovascular Disease
Type 2 Diabetes
Osivelotor
for Liver Disease
The purpose of this study is to understand how Osivelotor is processed in people with loss of liver function. This study is seeking participants that are: stable loss of liver function with mild or moderate severity none of underlying conditions possibly affecting the study medicine being absorbed by the body All participants will receive one amount of Osivelotor by mouth before breakfast on the first day at the study clinic. A number of blood samples will be collected to understand how Osivelotor is changed and removed from the body. Participants will also have to undergo physical examination and other tests. This will help to understand if Osivelotor is safe. Participants will take part in the study for a maximum of 112 days. During this time, participants will have to stay onsite for 5 days. There will be 5 study visits at the study clinic.
Recruiting1 award Phase 1
Lorlatinib
for Liver Dysfunction
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Lorlatinib) in health participants. This study is seeking participants who: Must be male or female of 18 to 75 years of age, inclusive at the time of the study. Are willing and able to comply with all scheduled visits, treatment plan, and other study procedures. Have a BMI (body mass index) of 17.5 to 40 kg/m2; and a total body weight >50 kg (110 lb). Are capable of giving signed informed consent document. All participants in this study will receive Lorlatinib. Participants will be placed into 1 of 3 cohorts based on their hepatic (liver) function. Participants will take Lorlatinib once by mouth. We will examine the experiences of people receiving the study medicine. This will help us determine if the study medicine is safe and effective. Participants will take part in this study for up to 35 days.
Recruiting1 award Phase 16 criteria
LY3849891
for Non-alcoholic Fatty Liver Disease
The main purpose of this study is to evaluate the safety and tolerability of the study drug LY3849891 in participants with nonalcoholic fatty liver disease who have the patatin-like phospholipase domain-containing protein 3 (PNPLA3) I148M genotype. Blood tests and magnetic resonance imaging of the liver will be performed to determine the effects of LY3849891 on fatty liver disease. Blood tests will also determine how long it takes the body to eliminate LY3849891. This is a 2-part study and may last up to 32 weeks for each participant and may include 12 and 13 visits in parts A and B, respectively.
Recruiting0 awards Phase 1
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Frequently asked questions
What kind of research happens at Orange County Research Center?
Orange County Research Center is a medical facility located in Tustin, California. This center is recognized for care of Diabetes, Type 2 Diabetes, Liver Disease, Healthy Subjects, High Blood Pressure and other specialties. Orange County Research Center is involved with conducting 140 clinical trials across 84 conditions. There are 2 research doctors associated with this hospital, such as JOEL MICHAEL NEUTEL and Joel M Neutel.