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Norton Cancer Institute

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Louisville, Kentucky 40202
Global Leader in Lymphoma
Global Leader in Skin Cancer
Conducts research for Lung Cancer
Conducts research for Non-Small Cell Lung Cancer
Conducts research for T-Lymphoblastic Leukemia/Lymphoma
220 reported clinical trials
13 medical researchers
Photo of Norton Cancer Institute in LouisvillePhoto of Norton Cancer Institute in LouisvillePhoto of Norton Cancer Institute in Louisville

Summary

Norton Cancer Institute is a medical facility located in Louisville, Kentucky. This center is recognized for care of Lymphoma, Skin Cancer, Lung Cancer, Non-Small Cell Lung Cancer, T-Lymphoblastic Leukemia/Lymphoma and other specialties. Norton Cancer Institute is involved with conducting 220 clinical trials across 183 conditions. There are 13 research doctors associated with this hospital, such as John Hamm, MD, Don Stevens, MD, Jaspreet Grewal, MD, and Joseph Maly.

Area of expertise

1Lymphoma
Global Leader
Norton Cancer Institute has run 43 trials for Lymphoma. Some of their research focus areas include:
MYC positive
BCL2 positive
BCL6 positive
2Skin Cancer
Global Leader
Norton Cancer Institute has run 37 trials for Skin Cancer. Some of their research focus areas include:
Stage IV
Stage III
PD-L1 positive

Top PIs

Clinical Trials running at Norton Cancer Institute

Non-Hodgkin's Lymphoma
Multiple Myeloma
Lymphoma
Squamous Cell Carcinoma
Non-Small Cell Lung Cancer
B-Cell Lymphoma
Lung Cancer
Plasma Cell Neoplasm
Ovarian Cancer
Cervical Cancer
Image of trial facility.

RNK05047

for Cancer

This trial tests RNK05047, a new drug, on patients with advanced solid tumors, including DLBCL. The drug is given regularly through an IV to find the safest and most effective dose.
Recruiting1 award Phase 1 & 2
Image of trial facility.

REGN5837 + Odronextamab

for Aggressive B-Cell Lymphoma

The study is researching an experimental drug called REGN5837 in combination with another experimental drug, odronextamab (called "study drugs"). The aim of the study is to see how safe and tolerable the study drugs are, and to define the recommended dose for phase 2. The study is looking at several other research questions, including: * What side effects may happen from taking the study drugs * How much study drug is in the blood at different times * Whether the body makes antibodies against the study drugs (that could make the drugs less effective or could lead to side effects) * To find out how well the study drugs work against relapsed or refractory aggressive B-cell non-Hodgkin lymphomas (B-NHLs)
Recruiting1 award Phase 1
Image of trial facility.

Cema-cel

for B-Cell Lymphoma

This is a randomized, open-label study in adult patients who have completed standard first line therapy for large B-cell lymphoma (LBCL) and achieved a complete response or partial response suitable for observation, but who have minimal residual disease (MRD) as detected by the Foresight CLARITYâ„¢ Investigational Use Only (IUO) MRD test, powered by PhasED-Seqâ„¢. The purpose of the trial is to assess the efficacy and safety of consolidation with cemacabtagene ansegedleucel (cema-cel), an allogeneic CD19 CAR T product, as compared to standard of care observation. The study is conducted in 2 consecutive parts that will be enrolled continuously. In Part A of the study, participants with MRD are randomized to one of two treatment arms or an observation arm. Treatment includes cema-cel following a lymphodepletion regimen of fludarabine and cyclophosphamide administered with or without the anti-CD52 monoclonal antibody, ALLO-647. Part A will culminate with the selection of the lymphodepletion regimen to advance to Part B. Part B will evaluate the selected lymphodepletion regimen followed by cema-cel as compared with observation.
Recruiting1 award Phase 25 criteria

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Frequently asked questions

What kind of research happens at Norton Cancer Institute?
Norton Cancer Institute is a medical facility located in Louisville, Kentucky. This center is recognized for care of Lymphoma, Skin Cancer, Lung Cancer, Non-Small Cell Lung Cancer, T-Lymphoblastic Leukemia/Lymphoma and other specialties. Norton Cancer Institute is involved with conducting 220 clinical trials across 183 conditions. There are 13 research doctors associated with this hospital, such as John Hamm, MD, Don Stevens, MD, Jaspreet Grewal, MD, and Joseph Maly.
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security