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Montreal Heart Institute

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MONTREAL, Quebec H1T 1C8
Global Leader in Heart Failure
Global Leader in Atrial Fibrillation
Conducts research for Coronary Artery Disease
Conducts research for Myocardial Infarction or Heart Attack
Conducts research for Myocardial Ischemia
220 reported clinical trials
21 medical researchers
Photo of Montreal Heart Institute in MONTREALPhoto of Montreal Heart Institute in MONTREALPhoto of Montreal Heart Institute in MONTREAL

Summary

Montreal Heart Institute is a medical facility located in MONTREAL, Quebec. This center is recognized for care of Heart Failure, Atrial Fibrillation, Coronary Artery Disease, Myocardial Infarction or Heart Attack, Myocardial Ischemia and other specialties. Montreal Heart Institute is involved with conducting 220 clinical trials across 223 conditions. There are 21 research doctors associated with this hospital, such as Anita Asgar, Reda Ibrahim, MD, lena Rivard, MD, MSc, and Philippe Demers.

Top PIs

Clinical Trials running at Montreal Heart Institute

Heart Failure
Bleeding
Atrial Fibrillation
Stroke
Ascending Aortic Aneurysm
Type 2 Diabetes
Inflammation
Cardiovascular Disease
Heart Attack
Myocardial Infarction or Heart Attack
Image of trial facility.

Heart Surgery

for Coronary Artery Disease

The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy (STICH3C) trial is a prospective, unblinded, international multi-center randomized trial of 754 subjects enrolled in approximately 45 centers comparing revascularization by percutaneous coronary intervention (PCI) vs. coronary artery bypass grafting (CABG) in patients with multivessel/left main (LM) coronary artery disease (CAD) and reduced left ventricular ejection fraction (LVEF). The primary objective is to determine whether CABG compared to PCI is associated with a reduction in all-cause death, stroke, spontaneous myocardial infarction (MI), urgent repeat revascularization (RR), or heart failure (HF) readmission over a median follow-up of 5 years in patients with multivessel/LM CAD and ischemic left ventricular dysfunction (iLVSD). Eligible patients are considered by the local Heart Team appropriate and amenable for non-emergent revascularization by both modes of revascularization. The secondary objectives are to describe the early risks of both procedures, and a comprehensive set of patient-reported outcomes longitudinally.
Recruiting1 award N/A4 criteria
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Multidisciplinary Screening

for Heart Failure

The goal of this study is improve the screening of heart failure and identify patients early who are at risk of heart failure. The main question[s] it aims to answer are: • will an electronic health records (EHR) case finding algorithm for heart failure, followed by N-Terminal pro-brain natriuretic peptide (NT-proBNP) screening and artificial intelligence (AI) echocardiogram compared to usual care identify patients at risk for heart failure earlier than standard of care? Participants will be enrolled and randomized to either standard of care (SOC) or intervention arm: SOC arm: electronic health records will be reviewed over six months for assessments performed to identify heart failure. Intervention arm: blood sample for N-terminal prohormone of B-type natriuretic peptide (NT-proBNP) at local laboratory . For elevated NT-proBNP results (>125pg/ml) an artificial intelligence (AI) echocardiogram and 12 lead electrocardiogram (ECG) will be performed at study site (within 28 days of NT-proBNP result). EHR will be reviewed at six months
Recruiting1 award N/A11 criteria
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Ziltivekimab

for Heart Failure and Inflammation

The study is being done to see if ziltivekimab can be used to treat participants living with heart failure and inflammation. Participants will either get ziltivekimab (active medicine) or placebo (inactive substance that looks like the study medicine but does not contain any medicine). The treatment participants get is decided by chance. Participant's chance of getting ziltivekimab or placebo is the same. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study is expected to last for up to 1 year and 4 months.
Recruiting1 award Phase 3

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Frequently asked questions

What kind of research happens at Montreal Heart Institute?
Montreal Heart Institute is a medical facility located in MONTREAL, Quebec. This center is recognized for care of Heart Failure, Atrial Fibrillation, Coronary Artery Disease, Myocardial Infarction or Heart Attack, Myocardial Ischemia and other specialties. Montreal Heart Institute is involved with conducting 220 clinical trials across 223 conditions. There are 21 research doctors associated with this hospital, such as Anita Asgar, Reda Ibrahim, MD, lena Rivard, MD, MSc, and Philippe Demers.