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Maine Medical Center

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Portland, Maine 04102

Global Leader in Coronary Artery Disease

Global Leader in Ovarian Cancer

Conducts research for Cystic Fibrosis

Conducts research for Prostate Cancer

Conducts research for Fallopian Tube Cancer

319 reported clinical trials

21 medical researchers

Photo of Maine Medical Center in PortlandPhoto of Maine Medical Center in PortlandPhoto of Maine Medical Center in Portland

Summary

Maine Medical Center is a medical facility located in Portland, Maine. This center is recognized for care of Coronary Artery Disease, Ovarian Cancer, Cystic Fibrosis, Prostate Cancer, Fallopian Tube Cancer and other specialties. Maine Medical Center is involved with conducting 319 clinical trials across 454 conditions. There are 21 research doctors associated with this hospital, such as Eric C. Larsen, Matthew D. Cheney, Leslie Bradford, MD, and Christine Lu-Emerson.

Area of expertise

1

Coronary Artery Disease

Global Leader

Maine Medical Center has run 28 trials for Coronary Artery Disease.

2

Ovarian Cancer

Global Leader

Maine Medical Center has run 21 trials for Ovarian Cancer. Some of their research focus areas include:

BRCA1 positive
Stage III
Stage IV

Top PIs

Clinical Trials running at Maine Medical Center

Prostate Cancer

Lung Cancer

Ovarian Cancer

Breast Cancer

Esophageal cancer

Cancer

Atrial Fibrillation

Kidney Cancer

Breast cancer

Gastric cancer

Image of trial facility.

Apalutamide + Targeted Radiation

for Prostate Cancer

This phase III trial tests two questions by two separate comparisons of therapies. The first question is whether enhanced therapy (apalutamide in combination with abiraterone + prednisone) added to standard of care (prostate radiation therapy and short term androgen deprivation) is more effective compared to standard of care alone in patients with prostate cancer who experience biochemical recurrence (a rise in the blood level of prostate specific antigen \[PSA\] after surgical removal of the prostate cancer). A second question tests treatment in patients with biochemical recurrence who show prostate cancer spreading outside the pelvis (metastasis) by positron emission tomography (PET) imaging. In these patients, the benefit of adding metastasis-directed radiation to enhanced therapy (apalutamide in combination with abiraterone + prednisone) is tested. Diagnostic procedures, such as PET, may help doctors look for cancer that has spread to the pelvis. Androgens are hormones that may cause the growth of prostate cancer cells. Apalutamide may help fight prostate cancer by blocking the use of androgens by the tumor cells. Metastasis-directed targeted radiation therapy uses high energy rays to kill tumor cells and shrink tumors that have spread. This trial may help doctors determine if using PET results to deliver more tailored treatment (i.e., adding apalutamide, with or without targeted radiation therapy, to standard of care treatment) works better than standard of care treatment alone in patients with biochemical recurrence of prostate cancer.

Recruiting

2 awards

Phase 3

Image of trial facility.

Shorter vs Usual Radiation Therapy

for Prostate Cancer

This phase III trial compares stereotactic body radiation therapy (SBRT), (five treatments over two weeks using a higher dose per treatment) to usual radiation therapy (20 to 45 treatments over 4 to 9 weeks) for the treatment of high-risk prostate cancer. SBRT uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period of time. This trial is evaluating if shorter duration radiation prevents cancer from coming back as well as the usual radiation treatment.

Recruiting

2 awards

Phase 3

10 criteria

Image of trial facility.

Standard Therapy + Surgery/Radiation

for Prostate Cancer

This phase III trial studies how well standard systemic therapy with or without definitive treatment (prostate removal surgery or radiation therapy) works in treating participants with prostate cancer that has spread to other places in the body. Addition of prostate removal surgery or radiation therapy to standard systemic therapy for prostate cancer may lower the chance of the cancer growing or spreading.

Recruiting

2 awards

Phase 3

30 criteria

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