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Lucile Packard Children's Hospital Stanford University

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Palo Alto, California 94304

Global Leader in Cancer

Global Leader in Brain Tumor

Conducts research for Neuroblastoma

Conducts research for Acute Lymphoblastic Leukemia

Conducts research for Solid Tumors

418 reported clinical trials

44 medical researchers

Photo of Lucile Packard Children's Hospital Stanford University in Palo AltoPhoto of Lucile Packard Children's Hospital Stanford University in Palo AltoPhoto of Lucile Packard Children's Hospital Stanford University in Palo Alto

Summary

Lucile Packard Children's Hospital Stanford University is a medical facility located in Palo Alto, California. This center is recognized for care of Cancer, Brain Tumor, Neuroblastoma, Acute Lymphoblastic Leukemia, Solid Tumors and other specialties. Lucile Packard Children's Hospital Stanford University is involved with conducting 418 clinical trials across 851 conditions. There are 44 research doctors associated with this hospital, such as Jay Michael S. Balagtas, Robert Lowsky, MD, Gail L Wright, MD, and Sonia Partap, MD.

Area of expertise

1

Cancer

Global Leader

Lucile Packard Children's Hospital Stanford University has run 63 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage I
Stage II
2

Brain Tumor

Global Leader

Lucile Packard Children's Hospital Stanford University has run 53 trials for Brain Tumor. Some of their research focus areas include:

BRAF positive
Stage I
Stage II

Top PIs

Clinical Trials running at Lucile Packard Children's Hospital Stanford University

Acute Lymphoblastic Leukemia

Testicular cancer

Crohn's Disease

Brain Cancer

Brain Tumor

Neuroblastoma

Adrenoleukodystrophy

Pneumonia

Wilms Tumor

Ovarian Carcinoma

Image of trial facility.

Palbociclib + Chemotherapy

for Acute Lymphoblastic Leukemia

With this research study has following goals * To confirm the highest tolerable dose of palbociclib in combination with chemotherapy is safe and well-tolerated. * To learn more about side effects of palbociclib in combination with chemotherapy; * To learn more about the biological effects of palbociclib on the cells in your body

Recruiting

3 awards

Phase 1

21 criteria

Image of trial facility.

Levocarnitine

for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma

This phase III trial compares the effect of adding levocarnitine to standard chemotherapy versus (vs.) standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.

Recruiting

2 awards

Phase 3

Image of trial facility.

ECG-Guided Umbilical Vessel Catheterization

for Acute Lymphoblastic Leukemia

Umbilical venous catheters (UVC) are typically places with poor guidance and some radiological confirmation. Misplacement of the catheter could lead to its placement in other unintended anatomical areas such as the liver or the spleen, which could be detrimental in critically-ill infants. Our study aims at using a more non-invasive means of placing and continuously monitoring catheter placement using superficial electrocardiogram (ECG) tracings.

Recruiting

1 award

N/A

3 criteria

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