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Johns Hopkins University School of Medicine

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Baltimore, Maryland 21205

Global Leader in HIV Infection

Global Leader in Human Immunodeficiency Virus Infection

Conducts research for Amyotrophic Lateral Sclerosis

Conducts research for Sickle Cell Disease

Conducts research for Tuberculosis

389 reported clinical trials

50 medical researchers

Photo of Johns Hopkins University School of Medicine in BaltimorePhoto of Johns Hopkins University School of Medicine in BaltimorePhoto of Johns Hopkins University School of Medicine in Baltimore

Summary

Johns Hopkins University School of Medicine is a medical facility located in Baltimore, Maryland. This center is recognized for care of HIV Infection, Human Immunodeficiency Virus Infection, Amyotrophic Lateral Sclerosis, Sickle Cell Disease, Tuberculosis and other specialties. Johns Hopkins University School of Medicine is involved with conducting 389 clinical trials across 636 conditions. There are 50 research doctors associated with this hospital, such as Kenneth J. Cohen, Stacie L. Stapleton, Paul Rosenberg, MD, and Argye E Hillis, MD, MA.

Top PIs

Clinical Trials running at Johns Hopkins University School of Medicine

Ovarian Cancer

Traumatic Amputation

Diabetes

Acute Myeloid Leukemia

Peroneal Nerve Injury

Wounds and Injuries

Obsessive-Compulsive Disorder

Tourette syndrome

Hand Injuries

Dizziness

Image of trial facility.

Uterine Lavage Test

for Ovarian Cancer

The study aims to develop a test for early detection of ovarian cancer using DNA from a growth involving the ovary found in a washing of the uterus (womb), and proteins found in the blood. The samples of the wash and the blood will be taken before surgery. After surgery, doctors will determine whether the participant had ovarian cancer or a benign disease of the ovaries. The tests of the washings and the blood will be examined to see how much the participants with ovarian cancer can be separated from the participants with a benign ovarian disease by the tests. Small amounts from the washing and the blood samples will be sent to four sites for analysis. Statistical analyses of these data will compare tumor DNA found in the washing of the uterus with proteins in the blood to detect cases of ovarian cancer. The primary goal is to find tests that are mostly positive for cases of ovarian cancer and mostly negative for patients with benign disease. It is hoped that if the tests work for participants with symptoms of the disease that these tests will also work when testing women who have no symptoms. A new study would be needed to see if the tests worked in this situation. If the tests work, this could lead to increasing the number of cases detected in early stage disease and decreasing the number of cases detected in late stage disease. If this change in late stage is large, it will likely reduce deaths due to ovarian cancer.

Recruiting

1 award

N/A

3 criteria

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