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Golisano Children's Hospital of Southwest Florida
Claim this profileFort Myers, Florida 33908
Global Leader in Leukemia
Global Leader in Tumors
Conducts research for Lymphoblastic Leukemia-Lymphoma
Conducts research for Lymphoma
Conducts research for Lymphoid Leukemia
166 reported clinical trials
2 medical researchers
Summary
Golisano Children's Hospital of Southwest Florida is a medical facility located in Fort Myers, Florida. This center is recognized for care of Leukemia, Tumors, Lymphoblastic Leukemia-Lymphoma, Lymphoma, Lymphoid Leukemia and other specialties. Golisano Children's Hospital of Southwest Florida is involved with conducting 166 clinical trials across 307 conditions. There are 2 research doctors associated with this hospital, such as Emad K. Salman and Jeffrey S. Dome.Area of expertise
1Leukemia
Global LeaderStage II
Philadelphia chromosome positive
NTRK1 positive
2Tumors
Global LeaderStage IV
Stage I
Stage II
Top PIs
Emad K. SalmanGolisano Children's Hospital of Southwest Florida6 years of reported clinical research
Expert in Tumors
Expert in Leukemia
63 reported clinical trials
118 drugs studied
Jeffrey S. DomeChildren's National Medical Center6 years of reported clinical research
Expert in Tumors
Expert in Brain Tumor
62 reported clinical trials
109 drugs studied
Clinical Trials running at Golisano Children's Hospital of Southwest Florida
Acute Lymphoblastic Leukemia
Rhabdomyosarcoma
Acute Myeloid Leukemia
Leukemia
Germ Cell Tumors
Acute Leukemia
Osteosarcoma
Lymphoma
Lymphoblastic Leukemia-Lymphoma
Brain Tumor
Levocarnitine
for Chemotherapy-Related Liver Protection in Leukemia and Lymphoma
This phase III trial compares the effect of adding levocarnitine to standard chemotherapy vs. standard chemotherapy alone in protecting the liver in patients with leukemia or lymphoma. Asparaginase is part of the standard of care chemotherapy for the treatment of acute lymphoblastic leukemia (ALL), lymphoblastic lymphoma (LL), and mixed phenotype acute leukemia (MPAL). However, in adolescent and young adults (AYA) ages 15-39 years, liver toxicity from asparaginase is common and often prevents delivery of planned chemotherapy, thereby potentially compromising outcomes. Some groups of people may also be at higher risk for liver damage due to the presence of fat in the liver even before starting chemotherapy. Patients who are of Japanese descent, Native Hawaiian, Hispanic or Latinx may be at greater risk for liver damage from chemotherapy for this reason. Carnitine is a naturally occurring nutrient that is part of a typical diet and is also made by the body. Carnitine is necessary for metabolism and its deficiency or absence is associated with liver and other organ damage. Levocarnitine is a drug used to provide extra carnitine. Laboratory and real-world usage of the dietary supplement levocarnitine suggests its potential to prevent or reduce liver toxicity from asparaginase. The overall goal of this study is to determine whether adding levocarnitine to standard of care chemotherapy will reduce the chance of developing severe liver damage from asparaginase chemotherapy in ALL, LL and/or MPAL patients.
Recruiting2 awards Phase 3
Imatinib + Chemotherapy
for Acute Lymphoblastic Leukemia
This study is evaluating whether a combination of drugs may help treat patients with a specific type of leukemia.
Recruiting2 awards Phase 3
Blinatumomab + Chemotherapy
for Leukemia
This study is evaluating whether a combination of chemotherapy and a monoclonal antibody may be more effective than chemotherapy alone in treating patients with B-lymphoblastic leukemia or B-ly
Recruiting2 awards Phase 36 criteria
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Frequently asked questions
What kind of research happens at Golisano Children's Hospital of Southwest Florida?
Golisano Children's Hospital of Southwest Florida is a medical facility located in Fort Myers, Florida. This center is recognized for care of Leukemia, Tumors, Lymphoblastic Leukemia-Lymphoma, Lymphoma, Lymphoid Leukemia and other specialties. Golisano Children's Hospital of Southwest Florida is involved with conducting 166 clinical trials across 307 conditions. There are 2 research doctors associated with this hospital, such as Emad K. Salman and Jeffrey S. Dome.