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EDMONTON

Cross Cancer Institute

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EDMONTON, Alberta T6G 1Z2

Global Leader in Lung Cancer

Global Leader in Cancer

Conducts research for Breast Cancer

Conducts research for Prostate Cancer

Conducts research for Pancreatic Cancer

739 reported clinical trials

37 medical researchers

Photo of Cross Cancer Institute in EDMONTONPhoto of Cross Cancer Institute in EDMONTONPhoto of Cross Cancer Institute in EDMONTON

Summary

Cross Cancer Institute is a medical facility located in EDMONTON, Alberta. This center is recognized for care of Lung Cancer, Cancer, Breast Cancer, Prostate Cancer, Pancreatic Cancer and other specialties. Cross Cancer Institute is involved with conducting 739 clinical trials across 462 conditions. There are 37 research doctors associated with this hospital, such as Quincy Chu, Michael Chu, MD, Michael Kolinsky, and Samir I. Patel.

Area of expertise

1

Lung Cancer

Global Leader

Cross Cancer Institute has run 113 trials for Lung Cancer. Some of their research focus areas include:

Stage IV
Stage III
PD-L1 positive
2

Cancer

Global Leader

Cross Cancer Institute has run 103 trials for Cancer. Some of their research focus areas include:

Stage IV
Stage III
HER2 negative

Top PIs

Clinical Trials running at Cross Cancer Institute

Lung Cancer

Breast Cancer

Cancer

Bladder Cancer

Multiple Myeloma

Prostate Cancer

Pancreatic Cancer

Solid Tumors

Ovarian Cancer

Chronic Lymphocytic Leukemia

Image of trial facility.

Telisotuzumab Vedotin vs. Docetaxel

for Non-Small Cell Lung Cancer

This trial is testing a new drug called telisotuzumab vedotin to see if it can treat a specific type of lung cancer better than an existing drug. The study focuses on adults whose lung cancer has not responded to previous treatments. The new drug targets and kills cancer cells by attaching to a specific protein on their surface.

Recruiting

2 awards

Phase 3

12 criteria

Image of trial facility.

Sacituzumab Tirumotecan vs Standard Therapy

for Lung Cancer

The purpose of this study is to evaluate sacituzumab tirumotecan versus pemetrexed in combination with carboplatin for the treatment of epidermal growth factor receptor (EGFR)-mutated advanced non-squamous non-small cell lung cancer (NSCLC). Participants in this study have NSCLC that has continued to progress on prior treatment with EGFR tyrosine kinase inhibitors (TKIs). The primary hypotheses of this study are that sacituzumab tirumotecan is better than platinum-based doublet chemotherapy (pemetrexed and carboplatin) in regard to progression-free survival (PFS) and overall survival (OS).

Recruiting

2 awards

Phase 3

2 criteria

Image of trial facility.

Zongertinib

for Lung Cancer

This study is open to adults 18 years and older who have early-stage non-small cell lung cancer (NSCLC). Their cancer must have a specific change in a gene called HER2. Genes provide the instructions for making proteins, and this change leads to a faulty HER2 protein. People can join if their lung cancer was removed by surgery, and they have already received certain other anti-cancer treatments. The purpose of this study is to find out if a study medicine called zongertinib helps people with this type of cancer live longer without their cancer coming back after surgery, when compared to standard treatment. Zongertinib is being developed to target the faulty HER2 protein, which can cause cancer cells to grow. In this study, participants are assigned by chance to one of two treatment groups, with an equal chance of being in either group. One group takes the study medicine, zongertinib, by mouth once a day for up to 3 years. The other group receives a standard treatment, chosen by their doctor. This standard treatment may be an immunotherapy medicine given by infusion into a vein every 3 or 4 weeks for up to 1 year, or regular check-ups without active study medicine (observation). Participants can be in this study for up to about 11 years. During this time, they visit the study site regularly for check-ups and study-related tests. The frequency of these visits varies depending on their treatment and how long they have been in the study. In addition to visits at the study site, participants in some treatment groups will also have phone calls with the study team every 3 weeks to check on their health between their scheduled visits. Doctors check for any signs of cancer coming back using imaging scans (like CT or MRI scans); these scans are generally done every 3 months for the first 2 years, then every 6 months for the next 3 years, and then yearly. Participants also fill in questionnaires about their overall wellbeing, health and symptoms. Throughout the study, doctors also check participants' health and note any unwanted effects.

Recruiting

2 awards

Phase 3

6 criteria

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