Children's Hospital and Medical Center of Omaha

Summary

Children's Hospital and Medical Center of Omaha is a medical facility located in Omaha, Nebraska. This center is recognized for care of Cancer, Brain Tumor, Neuroblastoma, Soft Tissue Sarcoma, Rhabdomyosarcoma and other specialties. Children's Hospital and Medical Center of Omaha is involved with conducting 197 clinical trials across 347 conditions. There are 7 research doctors associated with this hospital, such as Jill C. Beck, Minnie Abromowitch, Chittalsinh Raulji, MD, and Sookyong Koh, MD, PhD.

Top PIs

Clinical Trials running at Children's Hospital and Medical Center of Omaha

Brain Tumor

Testicular cancer

Wilms Tumor

Burkitt Lymphoma

Neuroblastoma

Cancer

Leukemia

Acute Lymphoblastic Leukemia

Biphenotypic Leukemia

Acute Leukemia

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.

Recruiting

2 awards

Phase 3

Lower Radiotherapy Dose

for Brain Tumors

This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.

Recruiting

1 award

Phase 2

10 criteria

Health Information Collection

for Childhood Cancer

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

Recruiting

1 award

N/A

10 criteria