Cardinal Glennon Children's Medical Center

Summary

Cardinal Glennon Children's Medical Center is a medical facility located in Saint Louis, Missouri. This center is recognized for care of Brain Tumor, Solid Tumors, Neuroblastoma, Cancer, Leukemia and other specialties. Cardinal Glennon Children's Medical Center is involved with conducting 221 clinical trials across 364 conditions. There are 5 research doctors associated with this hospital, such as William Ferguson, MD, Nitin Chouthai, MD, Deepika Bhatla, MD, and Erik Masden, MD.

Top PIs

Clinical Trials running at Cardinal Glennon Children's Medical Center

Brain Tumor

Wilms Tumor

Neuroblastoma

Leukemia

Cancer

Langerhans Cell Histiocytosis

Low Grade Glioma

Osteosarcoma

Rhabdomyosarcoma

Burkitt Lymphoma

Selumetinib vs. Chemotherapy

for Brain Cancer

This trial is comparing a new drug, selumetinib, with standard chemotherapy to treat patients with a specific type of brain tumor. The patients do not have a certain genetic mutation and are not affected by a genetic disorder. Selumetinib works by blocking enzymes needed for tumor growth, while the standard drugs kill or stop tumor cells from dividing.

Recruiting

2 awards

Phase 3

Lower Radiotherapy Dose

for Brain Tumors

This phase II trial studies how well lower dose radiotherapy after chemotherapy (Carboplatin \& Etoposide) works in treating children with central nervous system (CNS) germinomas. Radiation therapy uses high energy x-rays, particles, or radioactive seeds to kill cancer cells and shrink tumors. Carboplatin is in a class of medications known as platinum-containing compounds. It works in a way similar to the anticancer drug cisplatin, but may be better tolerated than cisplatin. Carboplatin works by killing, stopping or slowing the growth of tumor cells. Etoposide is in a class of medications known as podophyllotoxin derivatives. It blocks a certain enzyme needed for cell division and DNA repair and may kill cancer cells. Researchers want to see if lowering the dose of standard radiotherapy (RT) after chemotherapy can help get rid of CNS germinomas with fewer long-term side effects.

Recruiting

1 award

Phase 2

10 criteria

Health Information Collection

for Childhood Cancer

This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.

Recruiting

1 award

N/A

10 criteria