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Blank Children's Hospital

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Des Moines, Iowa 50309
Global Leader in Cancer
Global Leader in Adult T-Cell Leukemia/Lymphoma
Conducts research for Lymphoma
Conducts research for Brain Tumor
Conducts research for Acute Lymphoblastic Leukemia
171 reported clinical trials
2 medical researchers
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Summary

Blank Children's Hospital is a medical facility located in Des Moines, Iowa. This center is recognized for care of Cancer, Adult T-Cell Leukemia/Lymphoma, Lymphoma, Brain Tumor, Acute Lymphoblastic Leukemia and other specialties. Blank Children's Hospital is involved with conducting 171 clinical trials across 336 conditions. There are 2 research doctors associated with this hospital, such as Joshua Lukenbill and Samantha L. Mallory.

Area of expertise

1Cancer
Global Leader
Blank Children's Hospital has run 56 trials for Cancer. Some of their research focus areas include:
Stage IV
Stage I
Stage II
2Adult T-Cell Leukemia/Lymphoma
Global Leader
Blank Children's Hospital has run 47 trials for Adult T-Cell Leukemia/Lymphoma. Some of their research focus areas include:
Philadelphia chromosome positive
Stage II
CD5 positive

Top PIs

Clinical Trials running at Blank Children's Hospital

Testicular cancer
Acute Lymphoblastic Leukemia
Cancer
Testicular Carcinoma
Adult T-Cell Leukemia/Lymphoma
Germ Cell Tumors
Ovarian Carcinoma
Ovarian Tumors
Ovarian Choriocarcinoma
Lymphoma
Image of trial facility.

Chemotherapy

for Cancer

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.
Recruiting2 awards Phase 326 criteria
Image of trial facility.

Chemotherapy + Radiation Therapy

for Brain Cancer

This phase II trial studies the best approach to combine chemotherapy and radiation therapy (RT) based on the patient's response to induction chemotherapy in patients with non-germinomatous germ cell tumors (NGGCT) that have not spread to other parts of the brain or body (localized). This study has 2 goals: 1) optimizing radiation for patients who respond well to induction chemotherapy to diminish spinal cord relapses, 2) utilizing higher dose chemotherapy followed by conventional RT in patients who did not respond to induction chemotherapy. Chemotherapy drugs, such as carboplatin, etoposide, ifosfamide, and thiotepa, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high energy x-rays or high-energy protons to kill tumor cells and shrink tumors. Studies have shown that patients with newly-diagnosed localized NGGCT, whose disease responds well to chemotherapy before receiving radiation therapy, are more likely to be free of the disease for a longer time than are patients for whom the chemotherapy does not efficiently eliminate or reduce the size of the tumor. The purpose of this study is to see how well the tumors respond to induction chemotherapy to decide what treatment to give next. Some patients will be given RT to the spine and a portion of the brain. Others will be given high dose chemotherapy and a stem cell transplant before RT to the whole brain and spine. Giving treatment based on the response to induction chemotherapy may lower the side effects of radiation in some patients and adjust the therapy to a more efficient one for other patients with localized NGGCT.
Recruiting1 award Phase 2

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Frequently asked questions

What kind of research happens at Blank Children's Hospital?
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
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Terms of Service·Privacy Policy·Cookies·Security
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security