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Behavioural Intervention

Neurofeedback (from fMRI and/or EEG) for Nicotine Addiction

N/A
Waitlist Available
Led By R. Alison Adcock, MD, PhD
Research Sponsored by Duke University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up to occur following the neurofeedback session, up to 30 minutes following the session
Awards & highlights

Study Summary

This trial aims to see if a non-medication intervention can increase motivation for non-drug rewards (like a favorite food) for people with and without nicotine dependence.

Eligible Conditions
  • Nicotine Addiction

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~collected once during the screening visit
This trial's timeline: 3 weeks for screening, Varies for treatment, and collected once during the screening visit for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in reward-related brain activation
Secondary outcome measures
Dopamine availability
Onset to smoking a cigarette

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Reward-related Brain Region FeedbackExperimental Treatment1 Intervention
Participants in this group will receive neurofeedback from a reward-related brain area (e.g., VTA, PFC) using EEG and/or fMRI during the experiment.
Group II: Noise ControlPlacebo Group1 Intervention
Participants in this group will receive sham neurofeedback. Participants will be debriefed at the end of the study.

Find a Location

Who is running the clinical trial?

Brain & Behavior Research FoundationOTHER
61 Previous Clinical Trials
2,755 Total Patients Enrolled
National Center for Advancing Translational Sciences (NCATS)NIH
324 Previous Clinical Trials
401,579 Total Patients Enrolled
1 Trials studying Nicotine Addiction
8 Patients Enrolled for Nicotine Addiction
National Institutes of Health (NIH)NIH
2,720 Previous Clinical Trials
7,494,237 Total Patients Enrolled
2 Trials studying Nicotine Addiction
280 Patients Enrolled for Nicotine Addiction
~6 spots leftby May 2025
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