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Cigarette Smoke for Air Pollution (THS04 Trial)

N/A

Waitlist Available

Led By Suzaynn F Schick, PhD

Research Sponsored by University of California, San Francisco

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be between 18 and 65 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline, 30 minutes, 3 hours, 2 days, 5 days

Awards & highlights

THS04 Trial Summary

This trial will study the health effects of inhaling vs. skin exposure to thirdhand cigarette smoke.

Eligible Conditions

Air Pollution
Smoke Inhalation
Pollution Exposure

THS04 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline, 30 minutes, 3 hours, 2 days, 5 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline, 30 minutes, 3 hours, 2 days, 5 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline, 30 minutes, 3 hours, 2 days, 5 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Changes in flow-mediated dilation (FMD) of the brachial artery, caused by pollution exposures, measured by ultrasound

Secondary outcome measures

Changes in trans-epidermal water loss caused by pollution exposures, comparing intact skin to tape-stripped skin

THS04 Trial Design

4Treatment groups

Experimental Treatment

Active Control

Placebo Group

Group I: Dermal Exposure to Thirdhand Cigarette SmokeExperimental Treatment1 Intervention

Participants will wear clothing that has been exposed to cigarette smoke, for 3 hours while breathing filtered, temperature and humidity controlled air.

Group II: Inhalational Exposure to Thirdhand Cigarette SmokeActive Control1 Intervention

Participants will breathe cigarette smoke aerosol that has been aged for 22 hours, for 3 hours while wearing clean clothing.

Group III: Inhalational Exposure to Secondhand Cigarette SmokeActive Control1 Intervention

Participants will breathe cigarette smoke aerosol that has been aged for 30 minutes, for 3 hours while wearing clean clothing.

Group IV: Clean Air ExposurePlacebo Group1 Intervention

Participants will breathe filtered, temperature and humidity controlled air while wearing clean clothing for 3 hours.

Do I qualify?Apply below to find out

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Who is running the clinical trial?

University of California, San FranciscoLead Sponsor

2,515 Previous Clinical Trials

15,244,401 Total Patients Enrolled

Tobacco Related Disease Research ProgramOTHER

25 Previous Clinical Trials

20,552 Total Patients Enrolled

Suzaynn F Schick, PhDPrincipal InvestigatorUniversity of California, San Francisco

1 Previous Clinical Trials

60 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is the current enrollment cap for this clinical trial?

"Affirmative. According to the clinicaltrials.gov, this medical experiment is actively searching for eligible candidates with a launch date of January 20th 2020 and an update of August 15th 2022. 66 patients need to be enrolled from one site."

Answered by AI

Is there an ongoing enrollment process for this clinical experiment?

"Affirmative. Clinicaltrials.gov reveals that this investigation is presently recruiting participants, having been initially posted on the 20th of January 2020 and last updated on August 15th 2022. 66 volunteers are needed to be recruited from a single site."

Answered by AI

Is this research endeavor currently accepting elder participants?

"To be eligible for this clinical trial, potential participants must be between 18 and 50 years old. For those outside of this age range, there are 3 trials that cater to minors under the age of 18, as well as 7 studies designed specifically with elderly patients in mind."

Answered by AI

What criteria must potential participants meet in order to be eligible for this experiment?

"To be eligible for the trial, applicants must have been exposed to contaminated air and should range from 18-50 years of age. According to the protocol, 66 individuals will be accepted into the experiment."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke

2020. "Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04013256.