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Intervention Arm for Chronic Kidney Disease (Kidney-CHAMP Trial)

N/A

Waitlist Available

Led By Khaled Abdel-Kader, MD

Research Sponsored by University of Pittsburgh

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up time to event analysis - until primary outcome or a competing event (death, medication management without dialysis, being moved to hospice care) was achieved or until the end of intervention period (max 39 months). cumulative % at 24 months reported

Awards & highlights

Kidney-CHAMP Trial Summary

This trial will test whether an Electronic Health Record-based Population Health Management intervention can improve care for patients with high-risk Chronic Kidney Disease.

Eligible Conditions

Chronic Kidney Disease

Kidney-CHAMP Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ time to event analysis - until primary outcome or a competing event (death, medication management without dialysis, being moved to hospice care) was achieved or until the end of intervention period (max 39 months). cumulative % at 24 months reported

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~time to event analysis - until primary outcome or a competing event (death, medication management without dialysis, being moved to hospice care) was achieved or until the end of intervention period (max 39 months). cumulative % at 24 months reported

This trial's timeline: 3 weeks for screening, Varies for treatment, and time to event analysis - until primary outcome or a competing event (death, medication management without dialysis, being moved to hospice care) was achieved or until the end of intervention period (max 39 months). cumulative % at 24 months reported for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Renal Failure Event Defined as Greater Than or Equal to 40% Decline in Estimated Glomerular Filtration Rate (eGFR) or Occurrence of End Stage Renal Disease (ESRD)

Secondary outcome measures

Hypertension (HTN) Control Outcome

Medication Safety: Gemfibrozil Exposure Days

Medication Safety: Glyburide Exposure Days Per Year

+3 more

Other outcome measures

Subgroup Analysis Hypertension (HTN) Control (Outcome 2) in Participants With Uncontrolled BP at Baseline (i.e., BP >130/80 at Baseline).

Subgroup Analysis: Use of Renin-Angiotensin-Aldosterone System Inhibitors (RAASi) (Outcome 3) in Participants Who Are Baseline Non-users of RAASi

Kidney-CHAMP Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Intervention ArmExperimental Treatment1 Intervention

Patients will receive a care bundle

Group II: Usual careActive Control1 Intervention

Patients in the usual care arm will continue to receive CKD care guided by their PCPs as per usual care practices (i.e., specialty consultation, pharmacotherapy, nurse education, etc. may be ordered by the PCP according to their usual practice).

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

University of PittsburghLead Sponsor

1,726 Previous Clinical Trials

16,304,147 Total Patients Enrolled

Vanderbilt University Medical CenterOTHER

859 Previous Clinical Trials

670,771 Total Patients Enrolled

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH

2,364 Previous Clinical Trials

4,313,806 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are octogenarians suitable candidates for this investigation?

"The criteria for patient inclusion in this clinical trial requires that they are aged 18 or above, but not exceeding 85."

Answered by AI

Am I qualified to partake in this clinical experimentation?

"This clinical trial is seeking 1650 volunteers aged 18 to 85 with chronic kidney disease (CKD). The applicants must meet the demands of: being over 18, no more than 85 years old, exhibiting a high-level risk in CKD based on validated external and internal models or displaying reduced eGFR levels or having experienced considerable declines in said values within the past year and half."

Answered by AI

Are individuals still able to partake in this investigation?

"According to information hosted on clinicaltrials.gov, the recruitment period for this study has ended; it was initially posted on May 1st 2019 and last updated on September 9th 2022. Despite that fact, there are currently 497 other medical trials searching for volunteers at present."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Kidney Coordinated Health Management Partnership

Manisha Jhamb 2019. "Kidney Coordinated Health Management Partnership". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03832595.