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Positive lower extremity ultrasound for Pulmonary Embolism

N/A
Waitlist Available
Led By Dorcas B Pinto, MD
Research Sponsored by Albany Medical College
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Clinical Concern for PE (moderate to high risk) that warrants imaging of the chest
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up for duration of study, about 1 year
Awards & highlights

Study Summary

At most institutions, the average patient with clinical concern for PE(pulmonary embolism) will have a CT angiogram(CTA) with contrast of the lungs performed to evaluate for a clot. However, CTA has risks including contrast- induced allergic reactions and nephropathy, as well as radiation which has been linked to development of cancer later in life. There is literature that has looked at using lower extremity doppler ultrasound first to evaluate for a DVT (deep venous thrombosis) in patients where there is concern for a PE. There is also literature showing that emergency medicine physicians can perform adequate lower extremity compression ultrasounds (LCUS), at the bedside with results similar to that of the ultrasound tech. The goal of this project is to fuse both principles by having emergency medicine physicians perform LCUS at the bedside, to help reduce CTA utilization in the evaluation of PE.

Eligible Conditions
  • Pulmonary Embolism
  • Deep Vein Thrombosis
  • Ultrasound

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~for duration of study, about 1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and for duration of study, about 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Absolute reduction in CT imaging to diagnose PE
Secondary outcome measures
Cost-analysis
Potential reduction in CT imaging to diagnose PE
Time to start of treatment

Trial Design

2Treatment groups
Experimental Treatment
Group I: Positive lower extremity ultrasoundExperimental Treatment1 Intervention
This group found to to have a deep venous thrombosis on lower extremity ultrasound will not have a CT of the chest ordered from the emergency department, and will be treated for the DVT and presumed PE.
Group II: Negative lower extremity ultrasoundExperimental Treatment1 Intervention
This group that does not have a deep venous thrombosis on lower extremity ultrasound will proceed to get the CT of the chest .

Find a Location

Who is running the clinical trial?

Albany Medical CollegeLead Sponsor
91 Previous Clinical Trials
11,197 Total Patients Enrolled
Dorcas B Pinto, MDPrincipal InvestigatorAlbany Medical College

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
~42 spots leftby May 2025