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Air/Oxygen Mixture for Pulmonary Atelectasis

N/A
Waitlist Available
Led By Neal Badner, MD, FRCP(C)
Research Sponsored by London Health Sciences Centre
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up intra-operative and post operative day 1 and 2 .
Awards & highlights

Study Summary

Patients scheduled for lung lobe resection using video assisted thoracic surgery will be randomly assigned to be ventilated with either only oxygen or a mixture of air and oxygen. The primary purpose of this study is to determine if the incidence of postoperative collapse (in the non-surgical lung) is decreased when using a mixture of air and oxygen compared to using only oxygen (which is our control measurement) during one-lung ventilation.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~intra-operative and post operative day 1 and 2 .
This trial's timeline: 3 weeks for screening, Varies for treatment, and intra-operative and post operative day 1 and 2 . for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The incidence of postoperative atelectasis
Secondary outcome measures
The incidence of intraoperative and postoperative hypoxia (SpO2 < 90%) .

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Air/Oxygen MixtureExperimental Treatment1 Intervention
Patients in this group will be ventilated with a mixture of air and oxygen during one lung ventilation.
Group II: OxygenActive Control1 Intervention
Patients in this group will be ventilated with only oxygen during one lung ventilation.

Find a Location

Who is running the clinical trial?

London Health Sciences CentreLead Sponsor
143 Previous Clinical Trials
49,892 Total Patients Enrolled
Neal Badner, MD, FRCP(C)Principal InvestigatorLondon Health Science Centre, University Of Western Ontario

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Atelectasis After Pulmonary Lobectomy: The Effect Of Air During One-Lung Ventilation (OLV) On Postoperative Atelectasis
2010. "Atelectasis After Pulmonary Lobectomy: The Effect Of Air During One-Lung Ventilation (OLV) On Postoperative Atelectasis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01289691.
All > Lung
~5 spots leftby May 2025
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