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Cognitive Behavioral Therapy for Osteoarthritis (SPAC Trial)

N/A

Waitlist Available

Led By Ellen Terry, PhD

Research Sponsored by University of Florida

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Symptomatic knee OA

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up baseline; day 2

Awards & highlights

SPAC Trial Summary

This trial is investigating whether reducing pain catastrophizing can help relieve pain in adults with knee osteoarthritis, and whether this differs between ethnic groups.

Who is the study for?

The SPAC-2 trial is for adults aged 45 to 85 with knee osteoarthritis experiencing pain. It's not suitable for those using daily opioids, with recent psychiatric hospitalization, pregnant or nursing women, significant knee surgeries like replacements, uncontrolled high blood pressure, certain neuropathies, more severe pain elsewhere than in the knee, heart disease or neurological diseases like Parkinson's.Check my eligibility

What is being tested?

This study tests a single session cognitive-behavioral intervention aimed at reducing pain catastrophizing against a control group receiving only pain education. The goal is to understand how changing thoughts about pain can affect actual pain experiences across different ethnic groups.See study design

What are the potential side effects?

Since this trial involves educational and behavioral interventions rather than medications or invasive procedures, side effects are minimal but may include temporary discomfort from discussing personal experiences of pain.

SPAC Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have knee pain due to arthritis.

SPAC Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ baseline; day 2

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~baseline; day 2

This trial's timeline: 3 weeks for screening, Varies for treatment, and baseline; day 2 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Change in Pain Catastrophizing Scale (PCS)

SPAC Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Pain Catastrophizing Reduction GroupExperimental Treatment1 Intervention

This group will be assigned to a 30-minute, single-session cognitive-behavioral intervention designed to reduce pain catastrophizing.

Group II: Pain Education GroupActive Control1 Intervention

This group will receive general information about the neurobiology of pain and knee OA.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Cognitive-Behavioral Intervention

2021

N/A

~300

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

National Institute of Neurological Disorders and Stroke (NINDS)NIH

1,346 Previous Clinical Trials

650,659 Total Patients Enrolled

2 Trials studying Osteoarthritis

26 Patients Enrolled for Osteoarthritis

University of FloridaLead Sponsor

1,349 Previous Clinical Trials

720,030 Total Patients Enrolled

16 Trials studying Osteoarthritis

11,165 Patients Enrolled for Osteoarthritis

Ellen Terry, PhDPrincipal InvestigatorUniversity of Florida

1 Previous Clinical Trials

10 Total Patients Enrolled

1 Trials studying Osteoarthritis

10 Patients Enrolled for Osteoarthritis

Media Library

Cognitive-Behavioral Intervention Clinical Trial Eligibility Overview. Trial Name: NCT04805190 — N/A

Osteoarthritis Research Study Groups: Pain Catastrophizing Reduction Group, Pain Education Group

Osteoarthritis Clinical Trial 2023: Cognitive-Behavioral Intervention Highlights & Side Effects. Trial Name: NCT04805190 — N/A

Cognitive-Behavioral Intervention 2023 Treatment Timeline for Medical Study. Trial Name: NCT04805190 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What criteria must patients meet to participate in this experiment?

"This trial is searching for 104 individuals aged 45 to 85 with a diagnosis of osteoarthritis in the knee. Eligibility requirements must be met before recruitment can begin."

Answered by AI

Does this research study accept participants below the age of 65?

"The age range for this medical experiment is restricted to between 45 and 85 years old. Conversely, there are 27 trials that cater specifically to those younger than 18, while 433 clinical studies attend to the needs of individuals above 65."

Answered by AI

How many participants have been recruited to join this clinical research study?

"Affirmative. According to the details posted on clinicaltrials.gov, this medical study was originally listed on October 15th 2021 and it is presently recruiting participants. A total of 104 individuals are needed for the trial that will take place at a single site."

Answered by AI

Is this research effort currently seeking volunteers?

"Affirmative, the information found on clinicaltrials.gov clearly states that this scientific research is actively searching for participants. The trial was initially posted in October 15th 2021 and amended later as recently as November 21st 2022, with a total of 104 patients being needed from one site."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Study of Pain Catastrophizing-2 (SPAC-2)

2021. "Study of Pain Catastrophizing-2 (SPAC-2)". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04805190.