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Increased Running for Knee Osteoarthritis (ORCA Trial)
ORCA Trial Summary
This trial will test whether running is safe for people with knee osteoarthritis.
ORCA Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowORCA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.ORCA Trial Design
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Who is running the clinical trial?
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- I have had a serious knee injury in the past.My X-rays show no signs of advanced arthritis.I have an inflammatory arthritis condition.I have had no knee pain in either knee for the last 12 months.My knee X-ray shows I have mild or moderate arthritis.I haven't used any corticosteroids or joint injections in the last 6 months.I have had surgery on at least one of my knees.I am over 40 years old.I have experienced knee pain most days in the last 3 months, especially when running or doing daily activities.I have a health condition that stops me from doing activities like running.
- Group 1: Running volume increase
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To what extent is this trial being conducted with participants?
"Affirmative. Clinicaltrials.gov has information showing that this medical trial went live as of December 1st 2019, and is actively recruiting participants with the last update occurring on May 16th 2022. The recruitment involves 80 patients from one centre."
What is the projected outcome of this clinical experiment?
"The primary objective of this trial, which will be monitored over the course of a baseline and 12-week timeframe, is to track changes in T2 relaxation time of the medial tibial cartilage. Secondary objectives include: recording weekly running distances through an online diary; assessing glycosaminoglycan concentration in lateral tibial cartilage with MRI (T1ρ); as well as monitoring for related changes in glycosaminoglycan concentration within the medial femoral cartilage via MRI (T1ρ)."
Are volunteers currently being recruited for this clinical experiment?
"Affirmative. The information posted on clinicaltrials.gov confirms that this medical study, initially advertised in December 2019, is still recruiting participants. 80 individuals are expected to take part at one site."
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