← Back to Search

Proton Beam Therapy

Proton Beam Radiotherapy for Brain Cancer

N/A

Waitlist Available

Led By Torunn I Yock, MD

Research Sponsored by Massachusetts General Hospital

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Participants must have undergone biopsy or attempted surgical resection and must have histologically confirmed medulloblastoma or pineoblastoma

Age range between 3 and 25 at the time of enrollment

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 3 years

Awards & highlights

Study Summary

This trialexamines the effects of proton beam radiation therapy for CNS cancer, which has been suggested to cause less damage to normal tissue than traditional photon radiation therapy.

Who is the study for?

This trial is for individuals aged 3-25 with a confirmed diagnosis of medulloblastoma or pineoblastoma, who have had surgery but no prior chemotherapy or radiation. They must start treatment within 35 days post-surgery and have a life expectancy over 3 months. Participants need adequate blood lab values and agree to use contraception.Check my eligibility

What is being tested?

The study is examining proton beam radiation therapy as an alternative to the traditional photon beam therapy for brain tumors. It aims to see if proton beams can effectively target the tumor while sparing more healthy tissue due to its precise delivery method.See study design

What are the potential side effects?

Proton beam radiation may cause side effects similar to other forms of radiation like fatigue, skin reactions at the treatment site, headaches, hair loss, nausea, and potential long-term effects on growth and cognitive function.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I have had a biopsy or surgery confirming I have medulloblastoma or pineoblastoma.

Select...

I am between 3 and 25 years old.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 3 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~3 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and 3 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Endocrine dysfunction

Neurocognitive Effects

Ototoxicity

Secondary outcome measures

Acute toxicity

Progression Free Survival

Treatment efficiency

Trial Design

1Treatment groups

Experimental Treatment

Group I: Proton Beam RadiationExperimental Treatment1 Intervention

Proton Beam Radiation

0 / 2Eligibility criteria met

Find a Location

Who is running the clinical trial?

Massachusetts General HospitalLead Sponsor

2,937 Previous Clinical Trials

13,198,960 Total Patients Enrolled

M.D. Anderson Cancer CenterOTHER

2,976 Previous Clinical Trials

1,789,418 Total Patients Enrolled

National Cancer Institute (NCI)NIH

13,687 Previous Clinical Trials

40,930,281 Total Patients Enrolled

Media Library

Proton Beam Radiation (Proton Beam Therapy) Clinical Trial Eligibility Overview. Trial Name: NCT01063114 — N/A

Brain Tumor Research Study Groups: Proton Beam Radiation

Brain Tumor Clinical Trial 2023: Proton Beam Radiation Highlights & Side Effects. Trial Name: NCT01063114 — N/A

Proton Beam Radiation (Proton Beam Therapy) 2023 Treatment Timeline for Medical Study. Trial Name: NCT01063114 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

To what population is enrollment in this trial open?

"This medulloblastoma trial seeks to recruit 90 participants aged between 3 and 25 years old."

Answered by AI

Is this research endeavor accommodating elderly participants?

"The terms of participation in this experiment necessitate that potential participants are between the ages of 3 and 25. Conversely, there are 89 trials available to those under 18 years old and 81 for elderly individuals above 65."

Answered by AI

Is enrollment available for this research endeavor?

"Unfortunately, the data hosted on clinicaltrials.gov reveals that this medical investigation is no longer taking in patients for participation; it was initially posted April 1st 2010 and most recently updated January 5th 2023. Notwithstanding, there are still 157 other trials currently actively searching for candidates."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

Torunn Yock, MD 2010. "Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01063114.

All > Medulloblastoma