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tDCS for Treatment-Resistant Depression
Study Summary
This trial is testing whether a noninvasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help treat major depressive disorder that has not responded to other treatments. tDCS involves passing a small electrical current through the brain to stimulate nerve cells. The trial will test different "doses" of tDCS (amount of current passed through the brain) to see if higher doses lead to greater improvements in depressive symptoms.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I am currently experiencing symptoms of psychosis.I have not taken medication for a neurological disorder in the last 3 years.I have a history of chronic headaches or migraines.My headaches or migraines have changed in the last two weeks.I haven't changed my mental health medication in the last 30 days.I have skin conditions or defects near where a medical device would be placed.I have been unconscious for over 5 minutes due to a head injury.I am between 18 and 65 years old.I have been diagnosed with major depressive disorder and currently have symptoms.I have had seizures in the past.I am currently experiencing a manic, hypomanic, or mixed episode of bipolar disorder.I experience severe discomfort or distress due to anxiety or PTSD.I have tried more than 6 antidepressants without success.I have open wounds near where the head electrodes would be placed.I have never been diagnosed with dementia or a major thinking/memory problem.I am experiencing depression due to another health condition.I have tried at least 3 different antidepressants without success.My depression did not improve after ECT, as confirmed by my doctor.
- Group 1: tDCS
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Who is eligible to partake in this clinical experiment?
"This clinical trial is accepting 25 patients aged 18 to 65 suffering from treatment-resistant depression. To be eligible, each person must have a HDRS-17 score of 17 or above at the baseline assessment."
Are there available vacancies in this research project for participants?
"The data on clinicaltrials.gov affirms that this specific medical investigation, which was established in April 2017 and last updated in July 2022, is currently not enrolling patients. However, there are over a thousand other trials actively seeking participants right now."
Does this trial welcome participants who are aged 50 or older?
"To be enrolled in this clinical trial, participants must meet the age criteria of being over 18 and below 65 years old."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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