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Guided Metoprolol Management for Atrial Fibrillation (PREEMPTIVE Trial)

N/A

Waitlist Available

Led By Miklos Kertai, MD. PhD

Research Sponsored by Vanderbilt University Medical Center

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from end of surgery to hospital discharge; usually 3-4 days

Awards & highlights

PREEMPTIVE Trial Summary

This trial is investigating whether personalized recommendations for the drug metoprolol, based on a patient's genetic makeup, will be more effective in reducing postoperative atrial fibrillation than the standard dosing recommendations.

Eligible Conditions

Post-operative Atrial Fibrillation

PREEMPTIVE Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from end of surgery to hospital discharge; usually 3-4 days

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from end of surgery to hospital discharge; usually 3-4 days

This trial's timeline: 3 weeks for screening, Varies for treatment, and from end of surgery to hospital discharge; usually 3-4 days for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Incidence of post-operative atrial fibrillation

Secondary outcome measures

Cost of interventions to control or treat post-operative atrial fibrillation

Incidence of adverse drug events

Length of hospital stay

+5 more

PREEMPTIVE Trial Design

1Treatment groups

Experimental Treatment

Group I: Pharmacogenetic-guided metoprolol managementExperimental Treatment1 Intervention

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Vanderbilt University Medical CenterLead Sponsor

863 Previous Clinical Trials

672,902 Total Patients Enrolled

10 Trials studying Atrial Fibrillation

5,095 Patients Enrolled for Atrial Fibrillation

Miklos Kertai, MD. PhDPrincipal Investigator - Vanderbilt University Medical Center

Vanderbilt University Hospital

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is enrollment available for this clinical trial?

"Affirmative. According to the information on clinicaltrials.gov, recruitment is currently underway for this medical trial which was first posted on March 5th 2021 and recently modified on March 10th 2022. The study needs 400 participants from one site in order to reach completion."

Answered by AI

What is the estimated size of participation in this medical experiment?

"Yes, the information confirms that this clinical trial is still in search of volunteers. First posted on March 5th 2021 and most recently updated on March 10th 2022, 400 individuals are needed to participate at a single location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery

Miklos Kertai 2021. "Preemptive Pharmacogenetic-guided Metoprolol Management for PostoperativeAtrial Fibrillation in Cardiac Surgery". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03943927.