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Propranolol + Memory Reactivation for PTSD
Study Summary
This trial will test if a memory-weakening intervention using propranolol can reduce PTSD symptoms when combined with a new technique to reactivate traumatic memories.
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I haven't started or changed any mental health medication in the last two months.I do not use drugs like opiates, marijuana, cocaine, amphetamines, or alcohol.I do not understand English, which is required for this trial.I am between 18-65, experienced a traumatic event, and have a high stress score.I understand the study's procedures, risks, and can give informed consent.I do not have heart issues, severe diabetes, or lung problems that would prevent me from undergoing PPNL.I am not taking medication that could dangerously interact with the study drug.We are looking for participants who have experienced a traumatic event, which may include those with PTSD.You have had a bad reaction to or have not followed instructions for taking a medication called a β-blocker in the past.During a specific test, participants need to meet certain mental and physical criteria to be randomly selected for the study.
- Group 1: Mismatch reactivation condition
- Group 2: Standard reactivation condition
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Drug Has Already Been Approved - The FDA has already approved this drug, and is just seeking more data.
- Pivotal Trial - The final step before approval, pivotal trials feature drugs that have already shown basic safety & efficacy.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this research endeavor recruiting individuals aged 45 or older?
"Eligibility criteria for this trial requires applicants to be younger than 65 years and of legal age."
Are researchers presently recruiting participants for this clinical trial?
"Unfortunately, according to clinicaltrials.gov this particular medical trial is not presently accepting patients. The first post was on August 1st 2023 with the last update on May 2nd 2023. However, there are still 328 other trials actively recruiting individuals at this time."
To what extent are patients eligible to participate in this research?
"To qualify for this medical trial, individuals must experience post-traumatic stress and be between 18 to 65 years of age. This research is seeking 80 participants in total."
What safety precautions are in place for patients utilizing Mismatch reactivation condition?
"Given that this treatment is approved and registered in a Phase 4 trial, our team at Power has assigned Mismatch reactivation condition with the maximum safety rating of 3."
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