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CPT + rTMS for PTSD
Study Summary
This trial will study whether adding rTMS to CPT improves PTSD and depression symptoms, as well as neurophysiological measures, in people with combat-related PTSD.
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I experienced a traumatic event within the last 3 months.You are a military veteran who served in conflicts after September 11, and you have been diagnosed with post-traumatic stress disorder (PTSD) specifically related to combat during that time.I cannot stop taking medication that increases my risk of seizures.I have a history of seizures.You have a history of mental health disorders such as bipolar disorder or psychosis.I have never had a severe traumatic brain injury or a high risk of seizures.I don't have epilepsy, severe head injuries, conditions that could cause seizures, brain tumors, or recent serious substance use issues.I do not have a history of stroke, brain blood vessel issues, dementia, Parkinson's, Huntington's, or multiple sclerosis.I am not fluent in English.I don't have any health issues that would make TMS treatment unsafe for me.I am not taking any medications or substances that increase my risk of seizures.You are at a high risk of attempting suicide.I have undergone rTMS treatment before.You have metal fragments or objects in or around your head that cannot be safely taken out.I am currently in a trial or therapy for PTSD.
- Group 1: Active rTMS Alone
- Group 2: Sham rTMS + CPT
- Group 3: Active rTMS + CPT
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this research project allow for participants who are senior citizens?
"According to the rules that determine who can and cannot participate in this research, the minimum age is 18 and the maximum age is 60."
Are there any restrictions on who is eligible to participate in this research?
"This trial will have 330 participants that suffer from moral injury. The ideal candidate is aged between 18 and 60, a veteran of post-9/11 military conflicts."
Are there still vacancies in this experiment for willing subjects?
"The clinical trial is ongoing and has been accepting candidates since May 1st, 2019. According to the information available on clinicaltrials.gov, the study's organizers made their most recent edits on October 20th, 2020."
Does Active rTMS have FDA approval to be used as a standalone treatment?
"Active rTMS Alone is considered a phase 2 trial, so it has some data supporting safety but not efficacy. This was given a score of 2."
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