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Immunotoxin

SL-401 for Chronic Myelomonocytic Leukemia

Phase 2
Waitlist Available
Research Sponsored by Stemline Therapeutics, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up through 12 months post last dose of tagraxofusp
Awards & highlights
No Placebo-Only Group

Summary

This trial is testing a new drug, tagraxofusp, to see if it is safe and effective in treating patients with either chronic myelomonocytic leukemia or myelofibrosis who have not responded to other treatments.

Eligible Conditions
  • Chronic Myelomonocytic Leukemia
  • Myelofibrosis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~through 12 months post last dose of tagraxofusp
This trial's timeline: 3 weeks for screening, Varies for treatment, and through 12 months post last dose of tagraxofusp for reporting.

Treatment Details

Study Objectives

Study objectives can provide a clearer picture of what you can expect from a treatment.
Primary study objectives
Evaluation of rate of response
Rate and severity of treatment-emergent adverse events

Awards & Highlights

No Placebo-Only Group
All patients enrolled in this study will receive some form of active treatment.

Trial Design

1Treatment groups
Experimental Treatment
Group I: Tagraxofusp (SL-401)Experimental Treatment1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
SL-401
2014
Completed Phase 2
~90

Find a Location

Who is running the clinical trial?

Stemline Therapeutics, Inc.Lead Sponsor
23 Previous Clinical Trials
6,425 Total Patients Enrolled
~8 spots leftby Nov 2025