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Protocolized Diuretic Therapy for Heart Failure (DICTATE-AHF Trial)
DICTATE-AHF Trial Summary
This trial is testing whether adding dapagliflozin to diuretic therapy can improve outcomes for people with or without type 2 diabetes who are hospitalized with acute decompensated heart failure.
- Heart Failure
- Type 2 Diabetes
DICTATE-AHF Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2023 Phase 3 trial • 240 Patients • NCT04298229DICTATE-AHF Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Could you provide more context on how Protocolized Diuretic Therapy has been studied before?
"Protocolized Diuretic Therapy was first trialed in 2014 at The University of Texas Health Science Center at San Antonio. So far, there have been a total of 174 completed trials. Currently, 67 trials are still active, with a large portion of these taking place in Jackson, Mississippi."
What is the mortality rate for people who undergo Protocolized Diuretic Therapy?
"Protocolized Diuretic Therapy has been studied in multiple phase 3 trials, so it has been determined to be safe."
What conditions usually warrant Protocolized Diuretic Therapy?
"Protocolized Diuretic Therapy is a broad category of treatment that encompasses pharmaceuticals, diet and lifestyle changes, and other monotherapies."
Are there other hospitals in the state conducting this trial?
"There are a total of 12 different clinical trial sites, 6 of which are actively recruiting patients. The locations include the University of Mississippi Medical Center in Jackson, INTEGRIS in Oklahoma City, and Saint Thomas West Hospital in Chapel Hill."
How many people fit the bill to join this experiment?
"That is accurate. According to the information provided on clinicaltrials.gov, this study is looking for 240 subjects at 6 different sites. The posting date was April 1st, 2020 and the most recent update was February 1st, 2022."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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