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SQ tree SLIT-tablet for Allergy (TreeTop Trial)

Phase 3

Waitlist Available

Led By Monika Gappa, Prof. Dr. Med.

Research Sponsored by ALK-Abelló A/S

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be younger than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 6 months

Awards & highlights

TreeTop Trial Summary

This trial is testing whether the medication is effective and safe to treat birch/tree pollen allergy in children and adolescents.

TreeTop Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 6 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~6 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and 6 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Pharmaceutical Preparations

Secondary outcome measures

Average daily medication score during the birch pollen season

Average daily medication score during the tree pollen season

Average daily symptom score during the birch pollen season

+2 more

TreeTop Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Intervention/treatmentExperimental Treatment1 Intervention

Sublingual allergy immunotherapy tablet, for daily administration SQ tree SLIT-tablet

Group II: PlaceboPlacebo Group1 Intervention

Gelatine (fish source), mannitol and sodium hydroxide

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

SQ tree SLIT-tablet

2015

Completed Phase 3

~1140

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

ALK-Abelló A/SLead Sponsor

76 Previous Clinical Trials

327,390 Total Patients Enrolled

ParexelIndustry Sponsor

305 Previous Clinical Trials

100,198 Total Patients Enrolled

Monika Gappa, Prof. Dr. Med.Principal InvestigatorEvangelisches Krankenhaus Düsseldorf

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research program looking for more participants?

"The information on clinicaltrials.gov suggests that this trial is looking for patients at this time. The trial was first announced on April 7th, 2021 and was last updated on August 12th, 2022."

Answered by AI

Is there a potential for SQ tree SLIT-tablet to have negative side effects for users?

"Data from Phase 3 clinical trials provides evidence of SQ tree SLIT-tablet's efficacy and safety, thus it received a score of 3 from our team."

Answered by AI

How many individuals are being given the chance to try this new treatment?

"The clinical trial is recruiting patients and the information is available on clinicaltrials.gov. The trial was first posted on 4/7/2021. It was last edited on 8/12/2022. They are looking for 1000 participants between 3 locations."

Answered by AI

Are elderly patients eligible to participate in this experiment?

"In order to take part in this clinical trial, potential patients must fall between the ages of 5 and 17. Out of the 242 total trials, 80 are for those under 18 and 162 are for seniors."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Study in Children and Adolescents With Birch Pollen-induced Rhinoconjunctivitis

2021. "A Study in Children and Adolescents With Birch Pollen-induced Rhinoconjunctivitis". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04878354.