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Protective Ventilation Strategies for One-Lung Ventilation During Thoracic Surgery
Study Summary
This trial is testing whether using higher levels of PEEP and recruitment maneuvers during thoracic surgery can prevent postoperative pulmonary complications better than using lower levels of PEEP without recruitment maneuvers.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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- I will need a breathing machine after my surgery.My asthma is not well-managed with current treatments.I have had surgery on my lung before.I have experienced lung-related complications after surgery.I am scheduled for a planned lung surgery with general anesthesia.I have a diagnosed or suspected muscle or nerve disease.I am having or have had procedures done on both sides of my body.My lung was separated using a method other than a double-lumen tube due to complications.I will have surgery lying on my stomach.I have had surgery on my esophagus, chest wall, or for lung transplantation only.I do not have severe heart failure or coronary disease.I am scheduled for a procedure that involves separating my lungs using a double lumen tube.I have a brain injury or tumor.My surgery is expected to last more than an hour.My surgery will mostly use one-lung ventilation.I am 18 years old or older.I have severe lung conditions like COPD, lung fibrosis, or emphysema.I have ongoing issues with very low blood pressure that doesn't improve.
- Group 1: THE LOWER PEEP LEVEL
- Group 2: THE HIGHER PEEP LEVEL
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How many participants can potentially take part in this research?
"Affirmative. According to the data on clinicaltrials.gov, this medical trial - which was first published in January 2017 and most recently amended in June 2022 - is actively enrolling patients. The study requires 2378 individuals from 2 different sites."
Are additional participants still being enrolled in this research initiative?
"Affirmative. According to information found on clinicaltrials.gov, this medical trial has been recruiting since January 1st 2017 and the last update was made on June 1st 2022. A total of 2378 people are needed for the study at two separate sites."
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