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VTX2735 for Periodic Syndrome (Explore Trial)
Explore Trial Summary
This trial will test if VTX2735 is safe/effective for treating Cryopyrin-Associated Period Syndrome (CAPS) in 10 patients, over a max of 4 weeks.
- Cryopyrin-Associated Periodic Syndromes
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Explore Trial Design
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Who is running the clinical trial?
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- You are not willing to stop taking anti-IL-1 therapy and deal with the symptoms of your disease getting worse.You have had a long-lasting or repeat infections.You have experienced at least one worsening of your condition during the screening period.You have severe symptoms or damage from a specific condition that makes it risky to stop taking a certain type of medication.You have hepatitis B, hepatitis C, HIV, AIDS, or active tuberculosis.You have been diagnosed with a specific subtype of a rare condition and have a mild form of the disease.
- Group 1: Cohort 2
- Group 2: Cohort 1
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How likely are individuals to experience adverse effects when participating in Cohort 1?
"Since Cohort 1 is currently being trialled in Phase 2, our team at Power has estimated its safety to be a score of 2. This rating indicates that there are data that support the drug's security, but no evidence indicating how effective it may be."
Is recruitment for this research project still taking place?
"Affirmative, the information hosted on clinicaltrials.gov indicates that this research project is currently looking for participants. Initially posted on March 18th 2023, and recently updated in April 11th of the same year; 10 patients will be accepted from two specific locations."
How many participants are engaged in this research?
"Affirmative. Information accessed via clinicaltrials.gov reveals that this research endeavour, which was originally posted on March 18th 2023, is currently enrolling participants. The investigation desires 10 patients to be recruited from 2 distinct medical facilities."
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