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Avelumab combined with Chemoradiation for Gastroesophageal Cancer
Study Summary
This trial will test if avelumab, when given with chemo and radiation, is safe and effective in treating patients with resectable esophageal and gastroesophageal cancer.
- Gastroesophageal Cancer
- Esophageal Cancer
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Is this trial presently seeking participants?
"As indicated on clinicaltrials.gov, recruitment for this trial has been suspended since March 28th 2022. Despite the fact that candidates are no longer being sought out in this study, there exist 1300 other investigations actively searching for volunteers at present."
What therapeutic uses is Avelumab combined with Chemoradiation typically prescribed for?
"The combination of Avelumab and Chemoradiation is effective in treating advanced endometrial cancer, melanoma, and metastatic neoplasms."
What aims is this clinical trial hoping to accomplish?
"This clinical trial aims to assess the tolerability and efficacy of a novel drug combination over 4 weeks post-resection. The primary outcome is pathological complete response rate, while secondary objectives include determining the number of participants who manage to finish their planned treatment, establishing an incidence rate for surgical complications through Wilson score method calculations and estimating R0 resection rates with 95% confidence intervals also calculated using said statistical technique."
To what extent have Avelumab and Chemoradiation been tested in tandem for medical treatments?
"At the moment, 1273 clinical trials related to Avelumab combined with Chemoradiation are ongoing. Of those studies, 341 have reached Phase 3. Shanghai is home to many of these experiments; however there are 69603 global locations conducting research for this treatment."
How many participants are participating in this clinical examination?
"Recruitment for this clinical trial has ended. It was first posted on May 29th 2018 and last edited on March 28 2021. If you're looking to join other studies, there are presently 27 trials recruiting patients with gastroesophageal cancer and 1273 involving Avelumab in combination with chemoradiation."
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