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Lidocaine for Pain Management (NeuCLA Trial)
NeuCLA Trial Summary
This trial will study how lidocaine affects pain processing and cognitive function by looking at brain activity.
NeuCLA Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.NeuCLA Trial Design
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
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- You regularly take pain medication for chronic pain at least three times a week.You have a past of seizures.You have a history of irregular heartbeats, like heart block or atrial fibrillation.You are very afraid of small or enclosed spaces.You are currently taking medication for a mental or neurological disorder as prescribed by your doctor.You have a heart condition called Wolff-Parkinson-White syndrome.You are pregnant.You have metal implants or piercings that cannot be removed.You have tattoos on your face that contain metal.You must have a regular body weight.You should be in good overall health.I'm sorry, but the criterion you provided seems to be incomplete. Could you please provide more context or information?You have a history of neurological or mental health disorders, including tremors, anxiety, or depression.You are taking medications for epilepsy, depression, mental illness, anxiety, attention deficit hyperactivity disorder (ADHD), sleep or pain on a regular basis.You have a significant sleep disorder called sleep apnea.
- Group 1: Lidocaine
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does this research trial have an age restriction?
"In compliance with the parameters of this clinical trial, all participants must be at least 18 years old and no older than 70."
How many individuals are being enrolled into the experiment?
"Yes, according to the clinicaltrials.gov information, this medical trial is currently recruiting participants. It was initially posted on November 22nd 2022 and updated lastly a week later on November 28th of that same year. The investigators are looking for 30 patients from one site to enrol in the study."
Are there any vacancies left for participants in this research project?
"According to the clinicaltrials.gov, this experiment is actively searching for participants with a posting date of November 22nd 2022 and last edited on November 28th 2022."
Who is eligible to partake in this medical research?
"This trial has a limited enrolment of 30, and is seeking adults aged between 18 and 70 who are suffering from pain. Additionally, these individuals must have an average body weight, be in good general health, and lack any specified conditions."
What is the intended outcome of this clinical experiment?
"This 4.5 minute trial intends to detect variances in resting-state functional connectivity when comparing drug-free and lidocaine conditions. The secondary objectives are evaluating the numerical rating scale (0-10) pain score difference between these two conditions, which would suggest a better outcome if there is an increase in pain scores during the drug free condition; assessing memory performance through signal detection metric d-prime; and determining whether there is a decrease in memory performance with lidocaine compared to the control group."
Has the administration granted authorization for intravenous lidocaine?
"Taking into account the limited evidence on both safety and efficacy, our team has assigned Lidocaine IV a score of 1."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
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