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Cardiac Myosin Activator

Caucasian Cohort - Dose 3 for Healthy Subjects

Phase 1
Waitlist Available
Research Sponsored by Bristol-Myers Squibb
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up day 1 up to day 28
Awards & highlights

Study Summary

This trial is testing how safe and well-tolerated a drug is, and how it moves in the body, in healthy people of Japanese and Caucasian backgrounds.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~day 1 up to day 28
This trial's timeline: 3 weeks for screening, Varies for treatment, and day 1 up to day 28 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Number of Participants with Adverse Events (AEs)
Number of Participants with Clinical Laboratory Abnormalities
Number of Participants with Electrocardiogram (ECG) Abnormalities
+2 more
Secondary outcome measures
Area Under the Plasma Concentration-time Curve From Time Zero Extrapolated to Infinite Time [AUC(0-inf)]
Maximum Observed Plasma Concentration (Cmax)
Time of Maximum Observed Plasma Concentration (Tmax)

Trial Design

4Treatment groups
Experimental Treatment
Group I: Japanese Cohort - Dose 3Experimental Treatment2 Interventions
Group II: Japanese Cohort - Dose 2Experimental Treatment2 Interventions
Group III: Japanese Cohort - Dose 1Experimental Treatment2 Interventions
Group IV: Caucasian Cohort - Dose 3Experimental Treatment2 Interventions
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Placebo
1995
Completed Phase 3
~2670
Danicamtiv
2023
Completed Phase 1
~100

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Bristol-Myers SquibbLead Sponsor
2,652 Previous Clinical Trials
4,130,798 Total Patients Enrolled
~15 spots leftby Jun 2025
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