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PalloV-CC for Colon Cancer
Study Summary
This trial is testing a new cancer vaccine by comparing it to past treatments. Patients will serve as their own controls by comparing their tumor's immunity before and after treatment. The study will enroll patients consecutively and in overlapping cohorts to test different doses of the vaccine.
- Colon Cancer
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
What are the main purposes of this experiment?
"This medical study aims to evaluate the Primary Immunologic Endpoint-Per Dosing Cohort Immunoscore of the tumour microenvironment over a period of approximately 1 year for all 4 cohorts enrolled. Additionally, Secondary objectives include comparing CD4+ and regulatory T cells expression within the Tumor Microenvironment, determining concordance between Immunoscore (scale range: low, intermediate, high) with other analytical tools such as gene expression data analysis (CIBERSORT) and T-cell receptor sequencing (Immunoseq), plus examining PD-L1 expression on tumor cells from pretreatment endoscopic biopsies, post"
How many people are eligible to take part in this clinical experiment?
"Affirmative. Evident from the information on clinicaltrials.gov, this medical trial is still accepting participants and was initially posted July 20 2019 with its most recent update made September 14 2022. The study necessitates 24 patients be recruited from a single location."
Has the FDA approved PalloV-CC for use in medical treatments?
"The clinical data surrounding PalloV-CC's safety is sparse, so it earned a score of 1."
Is there space for more participants in this research study?
"Affirmative. According to the information hosted by clinicaltrials.gov, this investigation is currently recruiting patients that meet its criteria. The study was first published on July 20th 2019 and recently updated on September 14th 2022; 24 individuals are needed from a single site for enrollment purposes."
Who else is applying?
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What portion of applicants met pre-screening criteria?
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