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Evolocumab for Brain Cancer
Study Summary
This trialwill test if a type of drug can cross the blood-brain barrier and be used to treat brain cancer.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2020 Phase 4 trial • 259 Patients • NCT03096288Trial Design
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Who is running the clinical trial?
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- I haven't had a stroke or eye bleeding unrelated to cancer surgery in the last 6 months.I finished IV antibiotics for an infection less than a week ago, except for preventive reasons.My liver function is not severely impaired.I have been diagnosed with a high-grade brain tumor.I am 18 years old or older.My liver tests are within the required range for starting evolocumab.My kidney function is good enough for treatment, based on a recent test.I agree to use effective birth control during and up to 1 month after the study.
- Group 1: Single dose of evolocumab
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is this a pioneering endeavor in the medical field?
"Developed by Hoffmann-La Roche, Evolocumab has been under clinical study since 2018. After a successful initial trial involving 435 participants, the drug received Phase 1 and 2 approval from regulators. Currently, 22 active trials are ongoing in 240 cities across 35 nations."
Are there available vacancies in this experiment for volunteers?
"The clinical trial, initially posted on October 8th 2021, is still searching for suitable patients according to the data found on clinicaltrials.gov. This information has been recently updated by our team as of October 13th 2022."
Approximately how many individuals are being admitted to participate in this research?
"Correct. Clinicaltrials.gov indicates that this clinical trial, which was issued on October 8th 2021, is actively recruiting patients. The research is trying to find 10 individuals at a single site."
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