NEUROCUPLE™ Patch for Pain After Oral Surgery
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial tests a patch called NEUROCUPLE™ to determine if it can reduce pain and decrease the need for opioids after wisdom teeth removal. Participants will receive either the active patch or a placebo patch that looks identical but is inactive. The trial seeks healthy individuals scheduled for the removal of partially or fully impacted wisdom teeth. As an unphased trial, this study provides a unique opportunity to contribute to innovative pain management research.
What prior data suggests that the NeuroCuple device is safe for pain relief after oral surgery?
Research shows that the NeuroCuple™ patch offers a promising way to manage pain after oral surgery, such as wisdom teeth removal. Studies have found that this patch effectively reduces pain and decreases the need for opioids, which often have serious side effects. In one study, patients using a similar patch reported no negative effects, suggesting that the NeuroCuple™ patch is well-tolerated.
The patch employs nanotechnology, using very tiny materials to enhance treatment. Previous research found that the NeuroCuple™ patch reduced pain levels by about 34% without causing major side effects. This suggests it is a safe option for managing post-surgery pain without relying on medications.12345Why are researchers excited about this trial?
The NEUROCUPLE™ Patch is unique because it offers a non-invasive, localized treatment option for managing pain after oral surgery, specifically wisdom teeth extraction. Unlike standard treatments like oral pain medications, which can affect the entire body and sometimes lead to unwanted side effects, the NEUROCUPLE™ Patch targets pain directly at the site of surgery. Researchers are excited about this treatment as it promises to reduce pain without the systemic effects of traditional painkillers, potentially offering a safer and more comfortable recovery experience.
What evidence suggests that the NEUROCUPLE™ Patch is effective for pain relief after oral surgery?
Research has shown that the NEUROCUPLE™ Patch, which participants in this trial may receive, might help ease pain after wisdom teeth removal. Studies also suggest it could reduce the need for opioid painkillers, commonly prescribed after such surgeries. The patch employs a special technology to target pain directly, potentially providing relief without drug side effects. Users of similar devices reported feeling less pain and recovering faster. Although more research is needed, early results are promising for those seeking alternative pain management methods.12356
Who Is on the Research Team?
Daniel Hawkins, MD
Principal Investigator
University of Pittsburgh
Are You a Good Fit for This Trial?
Inclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive the NeuroCuple or sham device for 2 days following wisdom teeth extraction
Follow-up
Participants are monitored for pain, opioid use, and other outcomes post-extraction
What Are the Treatments Tested in This Trial?
Interventions
- NEUROCUPLE™ Patch
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
Placebo Group
This arm of subjects will receive the active NEUROCUPLE™ patch to wear for 2-days following their Wisdom Teeth Extraction procedure
This arm of subjects will receive the placebo (non-active, sham) patch to wear for 2-days following their Wisdom Tooth Extraction procedure
Find a Clinic Near You
Who Is Running the Clinical Trial?
nCap Medical
Lead Sponsor
University of Pittsburgh
Collaborator
Citations
NeuroCuple to Mitigate Post-Wisdom Teeth Extraction Opioid ...
The primary objectives are to determine whether the active NeuroCuple reduces postoperative pain and decreases opioid consumption compared to a ...
NeuroCuple to Mitigate Post-Wisdom Teeth Extraction ...
The primary objectives are to determine whether the active NeuroCuple reduces postoperative pain and decreases opioid consumption compared to a sham (placebo) ...
Role of the NeuroCuple™ Device for the Postoperative Pain ...
Therefore, we hypothesized that the NeuroCuple™ device might potentially reduce postoperative pain and opioid consumption in patients undergoing ...
Reducing Pain From Wisdom Molar Extractions
The investigators found that the TMNB relieved jaw pain stemming from these muscles, in a quick and sustained manner, even in patients whose pain following ...
Nanotechnology for Pain Management - PMC - NIH
This study suggested that compared to baseline, the application of a nanocapacitor-based Kailo™ pain relief patch on the pain site for 30 days ...
Non-Opioid Pain Management Options After Oral Surgery
How effective is aspirin for oral surgery pain? Aspirin can help, but it is usually less effective than ibuprofen for surgical dental pain.
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