RV Management After LVAD Implantation for Heart Failure
Trial Summary
What is the purpose of this trial?
This project evaluates right ventricle (RV) protective strategies after left ventricular assist device (LVAD) implantation.
Will I have to stop taking my current medications?
The trial information does not specify whether you need to stop taking your current medications.
What data supports the effectiveness of the treatment Standardized RV Management for managing right ventricular failure after LVAD implantation?
The research highlights that right ventricular failure (RVF) is a common complication after left ventricular assist device (LVAD) implantation, and effective management strategies are crucial. Standardized RV Management may include supportive therapies like pulmonary vasodilators and inotropes, which are known to help manage RVF by improving heart function and blood flow.12345
Is RV management after LVAD implantation safe for humans?
Managing right ventricular (RV) failure after left ventricular assist device (LVAD) implantation is generally safe when done with careful monitoring and appropriate interventions. Studies show that using minimally invasive techniques and new devices can reduce complications, although RV failure remains a risk that needs to be managed effectively.23678
How does the treatment for RV management after LVAD implantation differ from other treatments?
The treatment for RV management after LVAD implantation is unique because it involves a standardized approach to managing right ventricular failure, which includes optimizing RV function, using supportive therapies like pulmonary vasodilators and inotropes, and potentially employing surgical interventions such as RV assist devices. This approach is tailored to address the specific challenges of RV failure that occur after LVAD implantation, which are not fully addressed by existing treatments.127910
Research Team
Jonathan Grinstein, MD
Principal Investigator
University of Chicago
Eligibility Criteria
This trial is for adults over 18 who are getting a durable LVAD implant to help their heart pump blood, without needing extra mechanical support for the right side of their heart. It's not for pregnant individuals or those with certain devices already in their heart that they depend on.Inclusion Criteria
Exclusion Criteria
Timeline
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants undergo LVAD implantation and are randomized to either standardized or usual care RV management
Follow-up
Participants are monitored for safety and effectiveness after treatment, including hemodynamic monitoring and assessment of RV function
Treatment Details
Interventions
- Standardized RV Management
- Usual Care RV Management
Find a Clinic Near You
Who Is Running the Clinical Trial?
University of Chicago
Lead Sponsor